Results 81 to 90 of about 3,216 (261)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Investigation of the Effect of Restitution Coefficient on 3-Dimensional Rockfall Analyses

open access: yesDoğal Afetler ve Çevre Dergisi
Due to its geological, geomorphological and climatic characteristics, Türkiye frequently experiences natural disasters, among which rockfalls pose significant risks, causing considerable loss of life and property in many regions of the country.
İbrahim Uykun   +2 more
doaj   +1 more source

Inelastic impact and the coefficient of restitution

open access: yesJournal of Engineering Research, 2016
A model for the impact between a structurally deformable sphere and a rigid flat surface is presented. It includes a nonlinear contact element that accounts for energy loss due to local plastic deformation or flattening of the sphere, a viscous element that accounts for energy loss due to wave propagation and/or damping, and a linear stiffness element ...
Christoforou, Andreas P.   +1 more
openaire   +2 more sources

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Unloading properties based elastoplastic continuous contact force model: Restitution and stiffness characterization

open access: yesAIP Advances
A nonlinear contact force model is developed for spherical elastoplastic impacts. The nonlinear contact force model is constructed based on an existing piecewise model and the other based on the force–displacement diagram. The energetic impact law of the
Khalid Alluhydan
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park   +5 more
wiley   +1 more source

Temperature Dependence of the Coefficient of Restitution for a Rubber Ball

open access: yesInternational Scholastic Journal of Science, 2010
The relationship between the temperature and the coefficient of restitution of a polybutadiene superball was investigated. The ball was released from a fixed height and tracked with a motion detector as it bounced.
Yoshitaka Tamiya
doaj  

Research on quantification of low-impact response and damage thresholds in mangoes

open access: yesHuanan Nongye Daxue xuebao
ObjectiveTo reveal the damage patterns of mangoes under low-velocity impact, and provide a theoretical basis for harvest and postharvest buffer design to reduce losses.MethodThe free-fall test was conducted with a factorial design using Vietnamese green ...
Jieli DUAN   +5 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

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