Results 171 to 180 of about 1,106,370 (306)

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Internal Aspiration in Macular Hole Surgery: A Retrospective Comparative Study

Journal of Ophthalmology
Ke Xu, Yanfeng Liao, Dan Li, Shuang Cui, Xuefeng Feng, Changguan Wang, Huijin Chen   +6 more
doaj   +1 more source

Quantum Fisher Information-Guided Diffusion Refinement for Fuzzy and Uncertain Surveillance Regions. [PDF]

Entropy (Basel)
Alam S, Makhija P, Saudagar AKJ, Albathan M.   +3 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Managing for post-disturbance recovery. Lessons from active and passive restoration approaches in mountain forests.

When large and severe disturbances affect mountain forests, their ability to provide fundamental ecosystem services may be impaired for a long time. Indeed, in the Alps, forested slopes exert a crucial protective function and rapidly restoring the forest
Emanuele Lingua, Davide Marangon, Giulia Mantero, Raffaella Marzano, Nicolò Anselmetto, Matteo Garbarino, Flavio Taccaliti, Paul Richter, Matteo Domanico, Tommaso Baggio   +9 more
core  

Practitioners' perceptions on ecological restoration: activities, challenges and solutions on two small oceanic islands. [PDF]

PeerJ
Baguette FMMP, Baider C, Merven R, Florens FBV.   +3 more
europepmc   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Hydromorphological Restoration of Streams Does Not Ensure the Recovery of Ecosystem Functioning. [PDF]

Glob Chang Biol
Haase U, Allen DC, Anlanger C, Boëchat IG, Mendoza-Lera C, Cross WF, Ebeling P, Fernandes Cunha DG, Fink P, Finkler N, Gücker B, Lorke A, Pasqualini J, Patrick CJ, Peipoch M, Schröder O, Sponseller R, von Schiller D, Weitere M, Brauns M.   +19 more
europepmc   +1 more source

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

FEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini, Esmaeil Biazar, Davood Zaeifi, Reza Zeinali, Saeed Heidari‐Keshel, Amimasoud Hassanour, Helia Saheli, Arezou Mehrabi   +7 more
wiley   +1 more source