Results 71 to 80 of about 5,001 (238)

Forest Landscape Restoration: Who Decides? A Governance Approach to Forest Landscape Restoration

Natureza & Conservação, 2013
Forest landscape restoration is currently gaining momentum as a means of jointly addressing climate change and future agricultural demands. Forest landscape restoration does not aim to ‘just’ restore forests, but to restore them from a broader perspective on the landscape as a whole, allowing simultaneous restoration of the ecological and productive ...
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Designing Smart Urban Parks with Sensor-Integrated Landscapes to Enhance Mental Health in City Environments

Buildings
As mental health issues such as stress, anxiety, and depression become increasingly prevalent in urban populations, there is a critical need to embed restorative functions into the built environment.
Yuyang Cai, Yiwei Yan, Guohang Tian, Yiwen Cui, Chenfang Feng, Haoran Tian, Xiaxi Liuyang, Ling Zhang, Yang Cao   +8 more
doaj   +1 more source

Healthy campus by open space design: Approaches and guidelines

Frontiers of Architectural Research, 2014
This paper examines the architectural and landscape design strategies and intentions for green, open spaces facilities targeting stress alleviation for learning environments such as those of university campuses in a compact urban setting.
Stephen Siu Yu Lau, Zhonghua Gou, Yajing Liu   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Determination of Restorative Experiential Qualities and Design Attributes Because of Revealed to Recuperative Effects of Psychiatric Hospital Gardens

Forestist, 2013
Psychiatric hospital gardens should be designed as Open Space Therapy Units to provide contributions on treatment process. However assessment of recuperative effects of these units on patients is not easy.
Çiğdem Sakıcı, Mustafa Var
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Green Exposure and Restorative Quality of Campus Public Spaces: A Nonlinear Multi-Dimensional Visual Analysis Using Computer Vision

Land
Green exposure in public spaces plays a critical role in promoting mental health and well-being, especially for populations experiencing elevated psychological pressure in academically demanding environments such as university campuses. However, existing
Haiyuan Quan, Xiwei Xu, Huanchun Huang, Zihan Gao, Wei Ding, Ning Qiu, Xinyu Han   +6 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source