Results 41 to 50 of about 306,750 (308)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Physical restraint mouse models to assess immune responses under stress with or without habituation
STAR Protocols, 2021 Summary: Physical confinement, or restraint, is a psychological stressor used in rodent studies. A single restraint episode elevates blood corticosterone levels, a hallmark of stress responses.
Jian Xiang Ding +3 more
doaj +1 more source
Decreasing Duration of Mechanical Restraint Episodes by Increasing Registered Nurse Assessment and Surveillance in an Acute Psychiatric Hospital [PDF]
, 2018 Background Application of mechanical restraints is a high-risk emergency measure that requires psychiatric intensive care in order to assure patient safety and expedite release at the earliest opportunity.
Allen, Diane
core +1 more source
Chemical and Physical Restraint of Patients
Procedia - Social and Behavioral Sciences, 2016 AbstractProblem Statement: The physical and chemical restraint of patients, despite being often applied with no real scientific basis, has always been part of nursing practice in caring for the ill people.Research Questions: What is the level of knowledge over in nursing about physically and chemically restraining?Purpose of the Study: Evaluate the ...
Cunha, Madalena +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Frontiers in Psychiatry, 2022 BackgroundThe use of physical restraint on vulnerable people with learning disabilities and mental health problems is one of the most controversial and criticised forms of restrictive practice.
Alina Haines-Delmont +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Restraint use among selected hospitalized elderly patients in Cairo, Egypt
BMC Research Notes, 2017 Objective This study’s primary objective was to investigate the prevalence of physical and chemical restraint use in selected elderly hospitalized patients. Results This study was conducted in April 2014 in four major acute care hospitals.
Amira G. Eltaliawi +4 more
doaj +1 more source
Analysis of the Restraint Model for Mental Disorder Clients in Health Care Facilities
Jurnal Ners, 2020 Introduction: The reduction or elimination of restraint for psychiatric patients continues to be an area of concern and debate. The lack of accessible alternatives to restraint shows that nurses need to use restraints.
Sitti Sulaihah +2 more
doaj +1 more source
Hold on: physical restraint in residential child care [PDF]
, 2007 Guidance for developing best practice, policy and improved outcomes for children and young people in residential child care. Children in residential care can exhibit disturbed and violent behaviour which can result in them being aggressive to themselves ...
Kendrick, A., Steckley, L.
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