Results 41 to 50 of about 47,144 (261)

Analysis of the Restraint Model for Mental Disorder Clients in Health Care Facilities

Jurnal Ners, 2020
Introduction: The reduction or elimination of restraint for psychiatric patients continues to be an area of concern and debate. The lack of accessible alternatives to restraint shows that nurses need to use restraints.
Sitti Sulaihah, Siti Khadijah, Darni Darni   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Physical restraint practical behavior,cognitive status quo and its influencing factors analysis of nurses in ICU

Huli yanjiu, 2017
Objective:To investigate the physical restraint practice behavior and cognitive status quo of nurses in ICU and to analyze its influencing factors.Methods:A survey of 187 ICU nurses was conducted by using the selfmade ICU nurses’ physical restraint ...
周松, 饶国卉, 王建宁, 王婧, 查丽玲, 詹梦梅, 黄秋霞   +6 more
doaj  

Qualitative Analysis of Knowledge of Manager Nurses about Restraint Practices

Sağlık ve Hemşirelik Yönetimi Dergisi, 2018
INTRODUCTION: This study was conducted to evaluate the knowledge of manager service/ICU nurses about physical and chemical restraint practices. METHODS: In this study, a descriptive phenomenological method was used based on the concept of "restraint ...
Türkan Karaca, Semiha Aydın Özkan
doaj   +1 more source

Restraint in the Intensive Care Unit [PDF]

Journal of Neurocritical Care, 2015
An increasing number of patients are treated in the intensive care unit (ICU) due to advances in medicine. Usually, healthcare professionals decide on the patient’s care in order to save the patient’s life. Sometimes, these actions conflict with patients’
Jung Sun Lee
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Development of physical restraint scale for nurses in grave surgical department

Huli yanjiu, 2016
Objective：To develop an evaluation tool of knowledgeattitudepractice for nurse’s physical restraint in grave surgical department,and to construct a evaluation scale for measuring the knowledge,attitude and behavior level of nurse’s physical restraint in
陈巧玲, 林孔榕, 林阳, 黄卓凡
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source