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Properties of restricted randomization with implications for experimental design [PDF]

open access: yesJournal of Causal Inference, 2022
Recently, there has been increasing interest in the use of heavily restricted randomization designs which enforce balance on observed covariates in randomized controlled trials.
Nordin Mattias, Schultzberg Mårten
doaj   +2 more sources

A roadmap to using randomization in clinical trials

open access: yesBMC Medical Research Methodology, 2021
Background Randomization is the foundation of any clinical trial involving treatment comparison. It helps mitigate selection bias, promotes similarity of treatment groups with respect to important known and unknown confounders, and contributes to the ...
Vance W. Berger   +13 more
doaj   +2 more sources

The association between sedentary behavior and infertility: a population-based cross-sectional observational study and Mendelian randomization analysis [PDF]

open access: yesReproductive Biology and Endocrinology
Objective The relationship between sedentary behavior and infertility remains ambiguous and contentious. This study seeks to elucidate this association by analyzing data from the 2013–2018 National Health and Nutrition Examination Survey (NHANES ...
Yun Wang   +5 more
doaj   +2 more sources

A nonlinear, causal link between serum 25-hydroxyvitamin D and prolactin in type 2 diabetes: Evidence from clinical and Mendelian randomization analyses [PDF]

open access: yesMetabolism Open
Background: Type 2 diabetes mellitus is increasingly prevalent and often accompanied by vitamin D insufficiency. Prolactin, once considered solely lactogenic, has emerged as a metabolic regulator, yet its relationship with vitamin D in T2DM remains ...
Jing He   +4 more
doaj   +2 more sources

Randomized benchmarking with restricted gate sets [PDF]

open access: greenPhysical Review A, 2018
Standard randomized benchmarking protocols entail sampling from a unitary 2 design, which is not always practical. In this article we examine randomized benchmarking protocols based on subgroups of the Clifford group that are not unitary 2 designs. We introduce a general method for analyzing such protocols and subsequently apply it to two subgroups ...
Winton Brown, Bryan Eastin
openalex   +4 more sources

Relationship between daytime napping duration and pan-cancer risk: a prospective cohort study based on the China Health and Retirement Longitudinal Study (CHARLS) [PDF]

open access: yesJournal of Health, Population and Nutrition
Background In recent years, cancer has become a hot topic in the field of health management, and its etiology may be related to a variety of factors. Current research suggests that daytime napping duration is associated with variety of diseases, but few ...
Guoqing Li   +6 more
doaj   +2 more sources

Investigating the visceral adiposity–major depressive disorder link: a cross-sectional NHANES 2011–2014 analysis and Mendelian randomization study [PDF]

open access: yesEating and Weight Disorders
Background In recent years, the intricate interplay between physical health and mental well-being has garnered significant attention, specifically highlighting the potential influence of adipose tissue distribution, notably visceral adipose tissue (VAT ...
Mengying Hu, Fei Jiang
doaj   +2 more sources

Randomization methods and cluster size in cluster randomized trials conducted in elementary and high schools [PDF]

open access: yesVojnosanitetski Pregled, 2022
Background/Aim. Randomization allows for study groups to be formed so that they are similar in all characteristics except outcomes. The aim of this study was to examine the frequency of randomization methods and their effect on achieving baseline balance
Pajčin Mirjana   +3 more
doaj   +1 more source

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