Results 31 to 40 of about 5,213,227 (370)
Health researchers are familiar with the concept of trial power, a number that prior to the start of a trial is intended to describe the probability that the results of the trial will correctly conclude that the intervention has an effect.
Hubert Wong +2 more
doaj +1 more source
Discrete Optimization for Interpretable Study Populations and Randomization Inference in an Observational Study of Severe Sepsis Mortality [PDF]
Motivated by an observational study of the effect of hospital ward versus intensive care unit admission on severe sepsis mortality, we develop methods to address two common problems in observational studies: (1) when there is a lack of covariate overlap ...
Fogarty, Colin B. +3 more
core +2 more sources
Background Randomization procedure in randomized controlled trials (RCTs) permits an unbiased estimation of causal effects. However, in clinical practice, differential compliance between arms may cause a strong violation of randomization balance and ...
Annalisa Pezzi +4 more
doaj +1 more source
Sequential monitoring with conditional randomization tests
Sequential monitoring in clinical trials is often employed to allow for early stopping and other interim decisions, while maintaining the type I error rate.
Plamadeala, Victoria +1 more
core +1 more source
Background The population of adult patients with early-treated phenylketonuria (PKU) following newborn screening is growing substantially. The ideal target range of blood phenylalanine (Phe) levels in adults outside pregnancy is a matter of debate ...
Roman Trepp +8 more
doaj +1 more source
Efficient generation of random derangements with the expected distribution of cycle lengths
We show how to generate random derangements efficiently by two different techniques: random restricted transpositions and sequential importance sampling.
Mendonça, J. R. G.
core +1 more source
Background Intravenous (IV) fluid therapy is essential in the treatment of critically ill pediatric surgery and trauma patients. Recent studies have suggested that aggressive fluids may be detrimental to patients.
Vincent P. Duron +7 more
doaj +1 more source
Minimal cost multifactor experiments for agricultural research involving hard-to-change factors
Multifactor experiments are very common in agricultural research. Randomizing run orders in multifactor experiments often witness in large number of factorwise level changes which will increase the cost and time of the experiments.
BIJOY CHANDA +8 more
doaj +1 more source
Information transport and limits of optical imaging in the highly diffusive regime
Imaging in the highly diffusive regime lies at the heart of various optical medical imaging technologies and other applications such as imaging through fog.
Jack Radford, Daniele Faccio
doaj +1 more source
Rerandomization to improve covariate balance in experiments
Randomized experiments are the "gold standard" for estimating causal effects, yet often in practice, chance imbalances exist in covariate distributions between treatment groups.
Morgan, Kari Lock, Rubin, Donald B.
core +1 more source

