Results 81 to 90 of about 142,506 (314)
Planet formation in highly inclined binaries
, 2009 We explore planet formation in binary systems around the central star where the protoplanetary disk plane is highly inclined with respect to the companion star orbit.
F. Marzari +19 more
core +3 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Archives of Medical Science, 2006 All those who like experimentation are sooner or later faced with a need of random selection of elements or objects of interest that they want to study (persons, patients, animals, cells, etc.).
Cezary Watała
doaj
PLoS Genetics, 2023 Mendelian randomization (MR) has been increasingly applied for causal inference with observational data by using genetic variants as instrumental variables (IVs).
Zhaotong Lin, Haoran Xue, Wei Pan
doaj +1 more source
Mean-Variance Optimization in Markov Decision Processes [PDF]
, 2011 We consider finite horizon Markov decision processes under performance measures that involve both the mean and the variance of the cumulative reward. We show that either randomized or history-based policies can improve performance.
Mannor, Shie, Tsitsiklis, John
core +3 more sources
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
On Nearly Balanced Designs for Sensory Trials [PDF]
In sensory experiments, often designs are used that are balanced for carryover effects. It is hoped that this controls for possible carryover effects, like, e.g., a lingering taste of the products. Proper randomization is essential to guarantee the usual
Kunert, Joachim, Sailer, Oliver
core
Deceleration in The Micro Traffic Model and Its Application to Simulation for Evacuation from Disaster Area [PDF]
, 2011 Referring to the Nagel–Schreckenberg’s (NaSch) model, we have studied the impact of agent and diligent driver into the micro traffic model in the case of evacuation. This study is attention to the deceleration that added in the micro traffic model.
Kohei, Arai, Tri, Harsono
core +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source