Results 161 to 170 of about 179,539 (265)

Horizontal acquisition of the Type I restriction-modification system enhances bacterial pathogenicity by mediating methylation of transcription factor-encoding genes. [PDF]

Nucleic Acids Res
Ma J, Jiang X, Bi H, Li J, Ma X, Chi X, Tang Y, Liu Z, Li H.   +8 more
europepmc   +1 more source

Deletion of One Nucleotide within the Homonucleotide Tract Present in the hsdS Gene Alters the DNA Sequence Specificity of Type I Restriction-Modification System NgoAV [PDF]

, 2011
Monika Adamczyk-Popławska, Michał Lower, Andrzej Piekarowicz   +2 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Correction: A novel SfaNI-like restriction-modification system in Caldicellulosiruptor extents the genetic engineering toolbox for this genus. [PDF]

PLoS One
Swinnen S, Zurek C, Krämer M, Heger RM, Domeyer JE, Ziegler J, Svetlitchnyi VA, Läufer A.   +7 more
europepmc   +1 more source

Modular organization of related Archaeal plasmids encoding different restriction-modification systems inMethanobacterium thermoformicicum

, 1992
Jörk Nölling, Fredericus J. M. van Eeden, Rik I.L. Eggen, Willem M. de Vos   +3 more
openalex   +2 more sources

Phase-variable restriction/modification systems are required for Helicobacter pylori colonization [PDF]

, 2014
Jonathan C. Gauntlett, Hans‐Olof Nilsson, Alma Fulurija, Barry J. Marshall, Mohammed Benghezal   +4 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Families of restriction enzymes: an analysis prompted by molecular and genetic data for type ID restriction and modification systems

, 2001
Annette J. B. Titheradge
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Optimising Transformation Efficiency in Borrelia: Unravelling the Role of the Restriction-Modification System of Borrelia afzelii and Borrelia garinii. [PDF]

Int J Mol Sci
Ruivo M, Kovács NZ, Schötta AM, Stelzer T, Hermann L, Mündler V, Bergthaler A, Reiter M, Wijnveld M.   +8 more
europepmc   +1 more source