Results 271 to 280 of about 605,403 (299)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

RESTRICTION-MODIFICATION SYSTEMS AS GENOMIC PARASITES IN COMPETITION FOR SPECIFIC SEQUENCES ALONG DNA

, 1995
Kohji Kusano, Taku Naito, Naofumi Handa, Yuko Nakayama, Ichizo Kobayashi   +4 more
openalex   +1 more source

Bacterial restriction-modification systems: mechanisms of defense against phage infection. [PDF]

Biophys Rep
Kang H, Gao A, Zhu Y.
europepmc   +1 more source

A novel thermostable restriction modification system

openaire   +1 more source

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Restriction-modification systems in lactococcus lactis

Gene, 1995
Several restriction-modification (R-M) systems have been identified in Lactococcus lactis. Most of the systems have been plasmid encoded and function as phage-resistance mechanisms. At least five different type-II R-M systems, LlaAI, LlaBI, LlaCI, LlaDI and LlaEI, were identified in isolates from a mixed Cheddar starter culture.
N, Nyengaard, F K, Vogensen, J, Josephsen   +2 more
openaire   +2 more sources

Restriction–modification system in bacteriophage MB78

Biochemical and Biophysical Research Communications, 2003
Restriction-modification system is present in bacteria to protect the cells against phage infection. Interestingly, the bacteriophage MB78, a virulent phage of Salmonella typhimurium possesses restriction-modification system. Permissive host transformed with plasmid having the genomic fragment of MB78 carrying the putative restriction-modification ...
Deepti, Chaturvedi, Maharani, Chakravorty   +1 more
openaire   +2 more sources

Selfish Behavior of Restriction-Modification Systems

Science, 1995
Plasmids carrying gene pairs encoding type II DNA restriction endonucleases and their cognate modification enzymes were shown to have increased stability in Escherichia coli . The descendants of cells that had lost these genes appeared unable to modify a sufficient number of recognition sites in their chromosomes to
T, Naito, K, Kusano, I, Kobayashi
openaire   +2 more sources

The restriction-modification system inStreptomyces flavopersicus

Folia Microbiologica, 2001
To clone bifunctional vectors in streptomycetes, it was necessary to define the restriction-modification system of Streptomyces flavopersicus. Plasmid DNA from bifunctional vectors pIJ699 and pXED3-13, isolated from E. coli strains with different methylation systems: E. coli DH5 alpha (dam+ dcm+), E. coli MB5386 (dam dcm), E.
D, Lyutzkanova, M, Stoilova-Disheva, V, Peltekova   +2 more
openaire   +2 more sources