Results 101 to 110 of about 998,947 (335)

Type II Restriction of Bacteriophage DNA With 5hmdU-Derived Base Modifications

Frontiers in Microbiology, 2019
To counteract bacterial defense systems, bacteriophages (phages) make extensive base modifications (substitutions) to block endonuclease restriction.
Kiersten Flodman, Rebecca Tsai, Michael Y. Xu, Ivan R. Corrêa, Alyssa Copelas, Yan-Jiun Lee, Ming-Qun Xu, Peter Weigele, Shuang-yong Xu   +8 more
doaj   +1 more source

Tensor-restriction categories [PDF]

Theory and Applications of Categories 37(21):635-670, 2021, 2020
Restriction categories were established to handle maps that are partially defined with respect to composition. Tensor topology realises that monoidal categories have an intrinsic notion of space, and deals with objects and maps that are partially defined with respect to this spatial structure.
arxiv  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

The Torelli map restricted to the hyperelliptic locus [PDF]

arXiv, 2019
Let $g \geq 2$ and let the Torelli map denote the map sending a genus $g$ curve to its principally polarized Jacobian. We show that the restriction of the Torelli map to the hyperelliptic locus is an immersion in characteristic not $2$. In characteristic $2$, we show the Torelli map restricted to the hyperelliptic locus fails to be an immersion because
arxiv  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Assessment of groundwater quality for irrigation purpose using irrigation water quality index (IWQI)

Journal of Environmental Engineering and Landscape Management
Groundwater represents an important natural resource for sustaining life. This study was conducted to evaluate groundwater in the Doukkala region in Morocco, using the Irrigation Water Quality Index (IWQI) and uses Inverse Distance Weighting (IDW) in ...
Hefdhallah S. Al-Aizari, Fatima Aslaou, Osan Mohsen, Ali R. Al-Aizari, Abdel-Basit Al-Odayni, Naaser A. Y. Abduh, Abdul-Jaleel M. Al-Aizari, Eman Abo Taleb   +7 more
doaj   +1 more source

Using Linkage Maps as a Tool To Determine Patterns of Chromosome Synteny in the Genus Salvelinus

G3: Genes, Genomes, Genetics, 2017
Next generation sequencing techniques have revolutionized the collection of genome and transcriptome data from nonmodel organisms. This manuscript details the application of restriction site-associated DNA sequencing (RADseq) to generate a marker-dense ...
Matthew C. Hale, Garrett J. McKinney, Courtney L. Bell, Krista M. Nichols   +3 more
doaj   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Molecular Mapping of Restriction-Site Associated DNA Markers In Allotetraploid Upland Cotton.

PLoS ONE, 2015
Upland cotton (Gossypium hirsutum L., 2n = 52, AADD) is an allotetraploid, therefore the discovery of single nucleotide polymorphism (SNP) markers is difficult. The recent emergence of genome complexity reduction technologies based on the next-generation
Yangkun Wang, Zhiyuan Ning, Yan Hu, Jiedan Chen, Rui Zhao, Hong Chen, Nijiang Ai, Wangzhen Guo, Tianzhen Zhang   +8 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source