Results 111 to 120 of about 998,947 (335)

Meiotic maps of sockeye salmon derived from massively parallel DNA sequencing

open access: yesBMC Genomics, 2012
Background Meiotic maps are a key tool for comparative genomics and association mapping studies. Next-generation sequencing and genotyping by sequencing are speeding the processes of SNP discovery and the development of new genetic tools, including ...
Everett Meredith V   +2 more
doaj   +1 more source

Generalized logarithmic Gauss map and its relation to (co)amoebas [PDF]

open access: yesarXiv, 2012
We define the generalized logarithmic Gauss map for algebraic varieties of the complex algebraic torus of any codimension. Moreover, we describe the set of critical points of the logarithmic mapping restricted to our variety, and we show an analogous of Mikhalkin's result on the critical points of the logarithmic map restricted to a hypersurfaces.
arxiv  

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Theorems about includings for multivalued mappings [PDF]

open access: yesarXiv, 2013
This paper is devoted to studying of some properties of multivalued mappings in Euclidean space. There were proved theorems on a fixed point for multivalued mappings whose restrictions to some subset in the closure of a domain satisfy "a coacute angle condition" or "a strict coacute angle condition".
arxiv  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Biharmonic Riemannian maps [PDF]

open access: yesarXiv, 2010
We give necessary and sufficient conditions for Riemannian maps to be biharmonic. We also define pseudo umbilical Riemannian maps as a generalization of pseudo-umbilical submanifolds and show that such Riemannian maps put some restrictions on the base manifolds.
arxiv  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

A Dense Linkage Map of Lake Victoria Cichlids Improved the Pundamilia Genome Assembly and Revealed a Major QTL for Sex-Determination

open access: yesG3: Genes, Genomes, Genetics, 2018
Genetic linkage maps are essential for comparative genomics, high quality genome sequence assembly and fine scale quantitative trait locus (QTL) mapping.
Philine G. D. Feulner   +4 more
doaj   +1 more source

Representations of fundamental groups of algebraic manifolds and their restrictions to fibers of a fibration [PDF]

open access: yesarXiv, 2000
We use pluriharmonic maps to study representations of fundamental groups of algebraic manifolds. This approach is functorial in the sense that the restriction of such a map to a fiber of a fibration remains pluriharmonic, and on this basis, we can investigate the relation between the properties of the original representation and what can be inferred by
arxiv  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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