Results 111 to 120 of about 798,636 (312)

Physical Map of the Channel Catfish Virus Genome: Location of Sites for Restriction Endonucleases Eco RI, Hin dIII, Hpa I, and Xba I [PDF]

, 1979
S. Chousterman, Michel Lacasa, P. Sheldrick   +2 more
openalex   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein.

PLoS Pathogens, 2011
After entry into target cells, retroviruses encounter the host restriction factors such as Fv1 and TRIM5α. While it is clear that these factors target retrovirus capsid proteins (CA), recognition remains poorly defined in the absence of structural ...
Sadayuki Ohkura, David C Goldstone, Melvyn W Yap, Kate Holden-Dye, Ian A Taylor, Jonathan P Stoye   +5 more
doaj   +1 more source

pBR322 restriction map derived from the DNA sequence: accurate DNA size markers up to 4361 nucleotide pairs long [PDF]

, 1978
J. Gregor Sutcliffe
openalex   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Cleavage maps for human cytomegalovirus DNA strain AD169 for restriction endonucleases EcoRI, BglII, and HindIII [PDF]

, 1982
Deborah H. Spector, Lisa Hock, J C Tamashiro   +2 more
openalex   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

An Integrated BAC and Genome Sequence Physical Map of Phytophthora sojae

Molecular Plant-Microbe Interactions, 2006
Phytophthora spp. are serious pathogens that threaten numerous cultivated crops, trees, and natural vegetation worldwide. The soybean pathogen P. sojae has been developed as a model oomycete. Here, we report a bacterial artificial chromosome (BAC)-based,
Xuemin Zhang, Chantel Scheuring, Sucheta Tripathy, Zhanyou Xu, Chengcang Wu, Angela Ko, S. Ken Tian, Felipe Arredondo, Mi-Kyung Lee, Felipe A. Santos, Rays H. Y. Jiang, Hong-Bin Zhang, Brett M. Tyler   +12 more
doaj   +1 more source

Naturally occurring variation in the restriction map of the amy region of Drosophila melanogaster. [PDF]

, 1988
Charles H. Langley, Antony E. Shrimpton, Taisuke Yamazaki, Naohiko T. Miyashita, Yohtaro Matsuo, Charles F. Aquadro   +5 more
openalex   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source