Results 141 to 150 of about 834,305 (312)

Indoor localization and trajectory correction with point cloud-derived backbone map

open access: yesInternational Journal of Applied Earth Observations and Geoinformation
As a commonly used indoor internet-of-things (IoT) positioning method, fingerprinting is frequently carried out through the fusion of inertial and WiFi or magnetic data. Nevertheless, signals like magnetic intensity and WiFi received signal strength tend
Zhenqi Zheng   +6 more
doaj   +1 more source

Irreducible restrictions of closed mappings

open access: yesTopology and its Applications, 1998
By a result of \textit{N. Lashnev} [Sov. Math., Dokl. 6, 1504-1506 (1966); translation from Dokl. Akad. Nauk SSSR 165, 756-758 (1965; Zbl 0145.19603)], every continuous, closed surjection \(f:X\to Y\), with \(X\) paracompact and \(Y\) Fréchet, is inductively irreducible (i.e., there exists a closed \(X'\subset X\) such that \(f(X')=Y\) and \(f| X'\) is
openaire   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Goal-directed therapy: what is the goal again?

open access: yesPerioperative Medicine
Recent attention has focused on intraoperative hypotension (IOH) and hemodynamic instability. This enhanced awareness to limit IOH, combined with fluid restriction and increased vasopressor use, has been associated with an increase in postoperative acute
Amy Yerdon   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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