Irreducible algebraic sets of matrices with dominant restriction of the characteristic map [PDF]
, 2003 Marcin Skrzyński
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Prediction of Small for Gestational Age and Growth-Restricted Neonates at 35 to 36 Weeks of Gestation: A Multicenter Cohort Study. [PDF]
Medicina (Kaunas)Martin-Alonso R +10 more
europepmc +1 more source
MOLECULAR VARIATION FOR mtDNA HAPLOTYPES OF Drosophila melanogaster AND D. simulans NATURAL POPULATIONS BASED ON MORE ACCURATE RESTRICTION-SITE MAP [PDF]
, 2006 M. Abdel Megeed
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Evidence of <i>in-utero Mycobacterium avium</i> subsp. <i>paratuberculosis</i> infection in two pregnant goats: PCR detection, bacterial isolation, and molecular genotyping. [PDF]
J Vet SciLee HG +7 more
europepmc +1 more source
Improved algorithms for searching restriction maps
, 1991 Webb Miller, John Barr, Kenneth E. Rudd
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source