MOLECULAR VARIATION FOR mtDNA HAPLOTYPES OF Drosophila melanogaster AND D. simulans NATURAL POPULATIONS BASED ON MORE ACCURATE RESTRICTION-SITE MAP [PDF]
M. Abdel Megeed
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Eccrine Spiradenoma with Diffusion Restriction at MRI. [PDF]
Lakhani DA+4 more
europepmc +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Design and control of a low-cost non-backdrivable end-effector upper limb rehabilitation device. [PDF]
Li F+7 more
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
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Scaffolding and validation of bacterial genome assemblies using optical restriction maps [PDF]
Niranjan Nagarajan+2 more
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Effects of Acute Upper and Lower Body Resistance Exercise on Cardiovascular Response in Adult Women Through Blood Flow Restriction. [PDF]
Park CH.
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