FEBS Open Bio, EarlyView.d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada +3 more
wiley +1 more source
Complete genome sequence data of <i>Clostridium isatidis</i> BK32, a lignocellulose-degrading bacterium isolated from compost. [PDF]
Data BriefBorn P, Uke A, Kosugi A.
europepmc +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
High Molecular Diversity of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in Germany Revealed by Multitarget Genotyping. [PDF]
Int J Mol SciMöbius P, Price-Carter M, Köhler H.
europepmc +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
Bibliometric analysis and description of research trends on nutritional management in Alzheimer's disease patients (1988-2024). [PDF]
Front NutrMeng C, Li B, Wang Z, Peng Q.
europepmc +1 more source
FEBS Open Bio, EarlyView.The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo +4 more
wiley +1 more source
Cryo-EM structures of DNA-free and DNA-bound BsaXI: architecture of a Type IIB restriction-modification enzyme. [PDF]
Nucleic Acids ResShen BW +4 more
europepmc +1 more source
Genetic diversity and population structure of the Taigan dog breed
FEBS Open Bio, EarlyView.The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova +10 more
wiley +1 more source
FCMI-YOLO: An efficient deep learning-based algorithm for real-time fire detection on edge devices. [PDF]
PLoS OneLu J +6 more
europepmc +1 more source