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An algorithm for searching restriction maps
Bioinformatics, 1990This paper presents an algorithm that searches a DNA restriction enzyme map for regions that approximately match a shorter 'probe' map. Both the map and the probe consist of a sequence of address-enzyme pairs denoting restriction sites, and the algorithm penalizes a potential match for undetected or missing sites and for discrepancies in the distance ...
W, Miller, J, Ostell, K E, Rudd
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Least-squares method for restriction mapping
Gene, 1978A least-squares procedure has been developed to aid in deriving restriction-fragment maps once the order of cutsites has been determined. A computer program which carries out this method can be used to map either linear or circular molecules.
J L, Schroeder, F R, Blattner
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Improved algorithms for searching restriction maps
Bioinformatics, 1991We present algorithms for searching a DNA restriction enzyme map for a region that best matches a shorter 'probe' map. Our algorithms utilize a new model of map alignments, and extensive experiments prove our model superior to earlier approaches for certain applications. Let M be the number of map sites and P be the number of probe sites.
W, Miller, J, Barr, K E, Rudd
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Refining Restriction Enzyme Genome Maps
Constraints, 1997zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Optimization of Restriction Fragment DNA Mapping
Journal of Computational Biology, 1998Consider a mapping project in which overlap of clonal segments is inferred from complete multiple restriction digests. The fragment sizes of the clones are measured with some error, potentially leading to a map with erroneous links. The number of errors in the map depends on the number and types of enzymes used to characterize the clones.
A F, Siegel +4 more
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Quasicqnformal mappings with restrictions in measure
Ukrainian Mathematical Journal, 1993\textit{I. N. Pesin} [Dokl. Akad. Nauk SSSR 187, 740-742 (1969; Zbl 0215.128)] formulated theorems on existence, equicontinuity and completeness for classes with integral restrictions of a certain form. \textit{G. David} [Ann. Acad. Sci. Fenn., Ser. AI 13, No.
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Global Matching of Random Restriction Maps
Methodology And Computing In Applied Probability, 2000zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Long-range restriction mapping
1995Abstract Mapping large and complex genomes relies on techniques that permit the analysis and manipulation of long stretches of DNA, hundreds to thousands of kilobases in length. This has been achieved largely through the developments of pulsed field gel electrophoresis (PFGE)-allowing the resolution of large DNA fragments, and yeast ...
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Genomic long-range restriction mapping
Methods, 1990With the development of pulsed-field gel electrophoresis methods and the availability of rare-cutting restriction endonucleases, it has become possible to construct restriction maps spanning very large genomic regions. In the past few years, methods for the construction of long-range maps have been applied and refined in many different laboratories ...
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1992
An approach to high-resolution restriction-fragment DNA mapping, known as Multiple-Restriction-Enzyme mapping (MRE mapping), is present. This approach significantly reduces the uncertainty of clone placement by using clone ends to synchronize the position in of clones within different maps, each map being constructed from fragment-length data produced ...
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An approach to high-resolution restriction-fragment DNA mapping, known as Multiple-Restriction-Enzyme mapping (MRE mapping), is present. This approach significantly reduces the uncertainty of clone placement by using clone ends to synchronize the position in of clones within different maps, each map being constructed from fragment-length data produced ...
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