Results 121 to 130 of about 620,532 (331)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The Effect of Different Degrees of Ankle Dorsiflexion Restriction on the Biomechanics of the Lower Extremity in Stop-Jumping

Applied Bionics and Biomechanics
Purpose. The functional status of the ankle joint is critical during dynamic movements in high-intensity sports like basketball and volleyball, particularly when performing actions such as stopping jumps.
Zanni Zhang, Datao Xu, Xiangli Gao, Minjun Liang, Julien S. Baker, Yaodong Gu   +5 more
doaj   +1 more source

Identification and Mapping of Eastern Filbert Blight Resistance Quantitative Trait Loci in European Hazelnut Using Double Digestion Restriction Site Associated DNA Sequencing [PDF]

, 2019
Josh A. Honig, Megan Muehlbauer, John M. Capik, Christine Kubik, Jennifer Vaiciunas, Shawn A. Mehlenbacher, Thomas J. Molnar   +6 more
openalex   +1 more source

Learning Sheaf Laplacian Optimizing Restriction Maps

2024 58th Asilomar Conference on Signals, Systems, and Computers
Proc. 58th Annual Asilomar Conference on Signals, Systems, and Computers (Asilomar), Pacific Grove, CA, Oct. 27 - Oct.
Leonardo Di Nino, Sergio Barbarossa, Paolo Di Lorenzo   +2 more
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A novel method for effectively selecting fragments not associated with restriction sites for whole-genome genotyping

BMC Biology
Background Reduced representation sequencing (RRS) using Restriction site-associated DNA sequencing (RAD-seq) has become a widely adopted method for whole-genome genotyping, owing to its cost-effectiveness and applicability across species.
Peng Chen, Bipei Zhang, Sheng Zhao, Zhenghang Zhu, Yiming Yan, Haotian Chen, Hong Lu, Yong Xiang, Yongquan Li, Yuxiao Chang   +9 more
doaj   +1 more source

A Restriction Map of Cauliflower Mosaic Virus DNA (Strain PV 147). Mapping of the Cleavage Sites of HhaI, SacI, AvaI, PvuII, PstI, XbaI, EcoRI, BglII, HincII, HpaII and HindII + III [PDF]

, 1979
Michel Volovitch, Gabrielle DRUGEON, J.R. Degorce Dumas, Anne‐Lise Haenni, P. Yot   +4 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source