Results 131 to 140 of about 2,063,201 (347)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
DNA restriction site mapping of adenovirus type 16 with BamI, EcoRI, HpaI AND SalI [PDF]
Tamas M. Varsanyi +2 more
openalex +1 more source
Irreducible restrictions of closed mappings
By a result of \textit{N. Lashnev} [Sov. Math., Dokl. 6, 1504-1506 (1966); translation from Dokl. Akad. Nauk SSSR 165, 756-758 (1965; Zbl 0145.19603)], every continuous, closed surjection \(f:X\to Y\), with \(X\) paracompact and \(Y\) Fréchet, is inductively irreducible (i.e., there exists a closed \(X'\subset X\) such that \(f(X')=Y\) and \(f| X'\) is
openaire +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
A Unified Framework for Mapping Quantitative Trait Loci in Bivalent Tetraploids Using Single-dose Restriction Fragments: A Case Study from Alfalfa [PDF]
Chang‐Xing Ma +4 more
openalex +1 more source
A new method for straightening DNA molecules for optical restriction mapping.
H. Yokota +8 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

