Results 41 to 50 of about 162,034 (262)

Special features of RAD Sequencing data:implications for genotyping

open access: yes, 2012
Restriction site-associated DNA Sequencing (RAD-Seq) is an economical and efficient method for SNP discovery and genotyping. As with other sequencing-by-synthesis methods, RAD-Seq produces stochastic count data and requires sensitive analysis to develop ...
Fuentes-Utrilla, Pablo   +12 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

A family of conjugate gradient methods for large-scale nonlinear equations

open access: yesJournal of Inequalities and Applications, 2017
In this paper, we present a family of conjugate gradient projection methods for solving large-scale nonlinear equations. At each iteration, it needs low storage and the subproblem can be easily solved.
Dexiang Feng, Min Sun, Xueyong Wang
doaj   +1 more source

Finite Time Adaptive Neural Dynamic Surface Control of Nonstrict Feedback Nonlinear Systems Including Dead-Zone and Full State Restrictions

open access: yesIEEE Access, 2020
In this paper, finite time adaptive neural network (NN) tracking control is investigated for a class of uncertain nonstrict feedback systems with unknown dead-zone and unmodeled dynamics as well as full state restrictions.
Ziwen Wu, Tianping Zhang
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

On the restriction of the Fourier transform to polynomial curves [PDF]

open access: yes, 2007
We prove a Fourier restriction theorem on curves parametrised by the mapping P(t) = (P1(t),..., Pn(t)), where each of the P1,..., Pn is a real-valued polynomial and t belongs to an interval on which each of the P1,..., Pn "resembles" a ...
Dendrinos, S, Dendrinos, S.
core  

Physical mapping integrated with syntenic analysis to characterize the gene space of the long arm of wheat chromosome 1A [PDF]

open access: yes, 2013
Background: Bread wheat (Triticum aestivum L.) is one of the most important crops worldwide and its production faces pressing challenges, the solution of which demands genome information. However, the large, highly repetitive hexaploid wheat genome has
Federica Cattonaro (158236)   +70 more
core   +1 more source

Molecular Mapping of Restriction-Site Associated DNA Markers In Allotetraploid Upland Cotton.

open access: yesPLoS ONE, 2015
Upland cotton (Gossypium hirsutum L., 2n = 52, AADD) is an allotetraploid, therefore the discovery of single nucleotide polymorphism (SNP) markers is difficult. The recent emergence of genome complexity reduction technologies based on the next-generation
Yangkun Wang   +8 more
doaj   +1 more source

Signal-based optical map alignment.

open access: yesPLoS ONE, 2021
In genomics, optical mapping technology provides long-range contiguity information to improve genome sequence assemblies and detect structural variation.
Mehmet Akdel   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy