Results 71 to 80 of about 2,423,969 (313)
Linear representations of hyperelliptic mapping class groups
, 2020 Let $p:S\to S_g$ be a finite $G$-covering of a closed surface of genus $g\geq 1$ and let $B$ its branch locus. To this data, it is associated a representation of a finite index subgroup of the mapping class group $\operatorname{Mod}(S_g\smallsetminus B)$
Boggi, Marco
core
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
, 2006 The mixed spin-1/2 and spin-3/2 Ising model on the union jack lattice is solved by establishing a mapping correspondence with the eight-vertex model. It is shown that the model under investigation becomes exactly soluble as a free-fermion eight-vertex ...
Strecka, Jozef
core +1 more source
Increased sleep depth in developing neural networks: new insights from sleep restriction in children
Frontiers in Human Neuroscience, 2016 Brain networks respond to sleep deprivation or restriction with increased sleep depth, which is quantified as slow-wave activity (SWA) in the sleep electroencephalogram (EEG).
Salome Kurth +11 more
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
A Family of DNA Sequences is Reproducibly Rearranged in the Somatic Nucleus of \u3cem\u3eTetrahymena\u3c/em\u3e [PDF]
, 1986 A small family of DNA sequences Is rearranged during the development of the somatic nucleus in Tetrahymena. The family is defined by 266 bp of highly conserved sequence which restriction mapping, hybridization and sequence analysis have shown is shared ...
Allitto, Bernice A., Karrer, Kathleen M.
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Cre-assisted fine-mapping of neural circuits using orthogonal split inteins
eLife, 2020 Existing genetic methods of neuronal targeting do not routinely achieve the resolution required for mapping brain circuits. New approaches are thus necessary.
Haojiang Luan +3 more
doaj +1 more source