Results 71 to 80 of about 3,801,363 (334)
BMC Genomics, 2019 Background Restriction site-associated DNA sequencing (RADseq) has revolutionized the study of wild organisms by allowing cost-effective genotyping of thousands of loci.
David L. J. Vendrami +2 more
doaj +1 more source
Restriction maps in equivariant KK-theory [PDF]
Journal of K-Theory, 2011 AbstractWe extend McClure's results regarding restriction maps in equivariant K-theory to bivariant K-theory:Let G be a compact Lie group and A and B be G-C*-algebras. Suppose that KKHn(A, B) is a finitely generated R(G)-module for every H ≤ G closed and n ∈ ℤ. Then, if KKF*(A, B) = 0 for all F ≤ Gfinite cyclic, then KKG*(A, B) = 0.
openaire +4 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Reversible Discriminant Analysis
IEEE Access, 2018 Principal component analysis (PCA) and linear discriminant analysis (LDA) have been extended to be a group of classical methods in dimensionality reduction for unsupervised and supervised learning, respectively.
Lan Bai +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecular Plant-Microbe Interactions, 1997 The avirulence genes that have been identified in Magna-porthe grisea exhibit varying degrees of stability in infection assays. AVR1-MARA is considered one of the stable avirulence genes.
M. Alejandra Mandel +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
AGORA: Assembly Guided by Optical Restriction Alignment
BMC Bioinformatics, 2012 Background Genome assembly is difficult due to repeated sequences within the genome, which create ambiguities and cause the final assembly to be broken up into many separate sequences (contigs).
Lin Henry C +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source