Results 161 to 170 of about 167,652,239 (303)

From Biopiracy to Sustainable Knowledge Governance: Epistemic Justice and the Reconstruction of Resource Sovereignty in the Global South. [PDF]

Sci Eng Ethics
Dong Q.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Determinants of high-royalty contracts and the impact of stronger protection of intellectual property rights in Japan [PDF]

This paper first reviews how Japan has strengthened the protection of intellectual property rights (IPRs), focusing on the expansion of the patentable subject matter, the restriction of the possibility of compulsory licensing, stronger deterrence against
Sadao Nagaoka
core  

Fiscal decentralization, local government innovation preference, and enterprise technological innovation: Evidence from China. [PDF]

PLoS One
Tu J.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Subdividing the commons: the politics of property rights transformation in Kenya's Maasailand [PDF]

"This paper discusses the internal processes and decisions that characterized the transition from collectively held group ranches to individualized property systems among the Maasai pastoralists of Kajiado district in Kenya.
Mwangi, Esther
core  

Two decades of majoritarian hegemony and minority subordination within Indonesian religious governance amidst polarization. [PDF]

Front Sociol
Andhita PR, Novianti E, Sumartias S, Rahmat A.   +3 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Ending Abusive Patient- and Family-Initiated Relationships in Alberta Nursing Practice: The Case for a Nurse-Specific Regulatory Standard. [PDF]

Nurs Rep
Karczewski D, Karczewski T, Olsen M.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source