Results 121 to 130 of about 370,341 (298)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
ObjectiveThis study investigated whether body image mediates the link between mindfulness (state/trait) and restrictive eating behaviors.MethodsA 6-day daily survey of 65 females with restrictive eating patterns incorporated correlation, regression, and ...
Kequn Chu +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Macroeconomic co-ordination as an economic policy concept : opportunities and obstacles in the EMU [PDF]
This paper traces the euro zone?s inadequate macroeconomic performance in recent years back to the predominance of a restrictive macroeconomic policy mix based on a ?new monetarist? approach to economic policy.
Hein, Eckhard, Truger, Achim
core +4 more sources
Delimiting restrictive relative clauses
The paper proposes a classification of restrictive relative clauses.
Cabredo Hofherr, Patricia
core +1 more source
Measuring Restrictive Masculinity: Development and Implementation Within University Students
Restrictive masculinity is a rigid construct of how to define manliness that is associated with several health harms. The current study sought to develop a brief questionnaire to measure restrictive masculinity.
Jonathan K. Noel +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Nurses and Violence - Restrictive practices
The Australian College of Nursing (ACN) is committed to ensuring older people are provided safe, person-centred and high-quality care, where restrictive practices are used only as a last resort.
Carey Mather (14743540)
core

