Results 201 to 210 of about 1,204,120 (329)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Parallels between the chloro and methoxy groups for potency optimization. [PDF]

RSC Med Chem
Chiodi D, Ishihara Y.
europepmc   +1 more source

Outcomes of Restrictive Practice Review Meetings in an Acute Mental Health Unit: A Retrospective Before‐and‐After Study

Esario IV Daguman, Alison Taylor, Matthew Flowers, Richard Lakeman, Marie Hutchinson   +4 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Exploring How the Psychological Safety of Patients Is Impacted by Restrictive Practices in Inpatient Mental Healthcare: A Qualitative Study. [PDF]

Int J Ment Health Nurs
Griffin B, Johnson J, Vogt KS, Mizen E, Keyworth C, Baker J.   +5 more
europepmc   +1 more source

Do patients need to stay in bed all day in the Epilepsy Monitoring Unit? Safety data from a non-restrictive setting

, 2017
Laura Crăciun, Jørgen Alving, Elena Gardella, Daniella Terney, Pirgit Meritam, Melita Čačić Hribljan, Sándor Beniczky   +6 more
openalex   +2 more sources

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Liberal versus restrictive red blood cell transfusion thresholds in acute acquired brain injury: a systematic review and meta-analysis. [PDF]

BMJ Open
Sud S, Guyatt G, Angriman F, Friedrich JO, Scales DC, Turgeon AF, English S, Adhikari NK.   +7 more
europepmc   +1 more source

Hesitation to Seek Healthcare Among Immigrants in a Restrictive State Context [PDF]

Elizabeth Aranda, Liz Ventura Molina, Elizabeth Vaquera, Elsa M. Pichardo, Osaro Iyamu   +4 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source