Results 1 to 10 of about 2,183 (140)

Use of serum KL-6 level for detecting patients with restrictive allograft syndrome after lung transplantation. [PDF]

PLoS ONE, 2020
KL-6 is an antigen produced mainly by damaged type II pneumocytes that is involved in interstitial lung disease. Chronic lung allograft dysfunction (CLAD) after lung transplantation (LT) is a major concern for LT clinicians, especially in patients with ...
Cristina Berastegui, Susana Gómez-Ollés, Alberto Mendoza-Valderrey, Thais Pereira-Veiga, Mario Culebras, Victor Monforte, Berta Saez, Manuel López-Meseguer, Helena Sintes-Permanyer, Victoria Ruiz de Miguel, Carlos Bravo, Judit Sacanell, María-Antonia Ramon, Laura Romero, María Deu, Antonio Román   +15 more
doaj   +4 more sources

Development of a Multivariate Prediction Model for Early-Onset Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome in Lung Transplantation [PDF]

Frontiers in Medicine, 2017
BackgroundChronic lung allograft dysfunction and its main phenotypes, bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), are major causes of mortality after lung transplantation (LT).
Angela Koutsokera, Pierre J. Royer, Jean P. Antonietti, Andreas Fritz, Christian Benden, John D. Aubert, Adrien Tissot, Karine Botturi, Antoine Roux, Martine L. Reynaud-Gaubert, Romain Kessler, Claire Dromer, Sacha Mussot, Hervé Mal, Jean-François Mornex, Romain Guillemain, Christiane Knoop, Marcel Dahan, Paola M. Soccal, Johanna Claustre, Edouard Sage, Carine Gomez, Antoine Magnan, Christophe Pison, Laurent P. Nicod, The SysCLAD Consortium   +25 more
doaj   +4 more sources

Prognostic impact of restrictive ventilatory defects in chronic lung allograft dysfunction without restrictive allograft syndrome-like opacities: Stratification of emerging undefined and unclassified phenotypes [PDF]

JHLT Open
Background: Chronic lung allograft dysfunction (CLAD) remains a critical factor affecting post-lung transplant prognosis. While RAS-like opacities (RLO) are established as poor prognostic indicators, prognostic stratification of non-RLO CLAD cases ...
Taiki Fukuda, MD, PhD, Yusei Nakamura, MD, Yuki Ko, MD, PhD, Shu-Chi Tseng, MD, Staci M. Gagne, MD, Takeshi Johkoh, MD, PhD, Yi Li, PhD, David C. Christiani, MD, MPH, MS, Hiroya Ojiri, MD, PhD, Lynette Sholl, MD, Mizuki Nishino, MD, MPH, Hiroto Hatabu, MD, PhD, FACR   +11 more
doaj   +4 more sources

Radiological distribution patterns in restrictive chronic lung allograft dysfunction: Impact on survival across all phenotypes [PDF]

JHLT Open
Background: Restrictive chronic lung allograft dysfunction (CLAD) demonstrates poor outcomes after lung transplantation. However, the impact of radiological patterns on survival within a restrictive CLAD under the new International Society for Heart and ...
Taiki Fukuda, MD, PhD, Yusei Nakamura, MD, Shu-Chi Tseng, MD, Yuki Ko, MD, PhD, Staci M. Gagne, MD, Takeshi Johkoh, MD, PhD, Yi Li, PhD, David C. Christiani, MD, MPH, MS, Hiroya Ojiri, MD, PhD, Lynette Sholl, MD, Mizuki Nishino, MD, MPH, Hiroto Hatabu, MD, PhD   +11 more
doaj   +2 more sources

Donor-derived cell-free DNA in chronic lung allograft dysfunction phenotypes: a pilot study [PDF]

Frontiers in Transplantation
Long-term survival after lung transplantation is limited due to chronic lung allograft dysfunction (CLAD), which encompasses two main phenotypes: bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS).
H. Beeckmans, A. Pagliazzi, P. Kerckhof, R. Hofkens, F. Debackere, A. Zajacova, S. Bos, S. Bos, B. M. Vanaudenaerde, H. de Loor, M. Naesens, M. Naesens, R. Vos, R. Vos   +13 more
doaj   +2 more sources

Chronic lung allograft dysfunction post-lung transplantation: The era of bronchiolitis obliterans syndrome and restrictive allograft syndrome. [PDF]

World J Transplant, 2020
Yoshiyasu N, Sato M.
europepmc   +2 more sources

Bronchiolitis obliterans syndrome and restrictive allograft syndrome after lung transplantation: why are there two distinct forms of chronic lung allograft dysfunction? [PDF]

Ann Transl Med, 2020
Sato M.
europepmc   +3 more sources

Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction [PDF]

JHLT Open
Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung ...
Mary A. Neal, PhD, Saskia Bos, MD, PhD, Charlotte W. Holland, MRCP, Kieren G. Hollingsworth, Gerard Meachery, FRCP, Arun Nair, MD, FRCP, James L. Lordan, FRCP, Andrew J. Fisher, FRCP, PhD, Peter E. Thelwall, PhD   +8 more
doaj   +2 more sources

Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity? [PDF]

JHLT Open
Chronic graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation, with pulmonary chronic graft-versus-host disease (PcGvHD) particularly associated with a dismal prognosis. Lung transplantation (LuTx) is
Andrea Zajacova, MD, Hélène Schoemans, MD, PhD, Mark Greer, MD, MRCP, Hildegard Greinix, MD, Peter Jaksch, MD, Osnat Shtraichman, MD, Rayid Abdulqawi, MD, PhD, Are M. Holm, MD, PhD, Robin Vos, MD, PhD, Saskia Bos, MD, PhD   +9 more
doaj   +2 more sources

Survival of patients with advanced chronic lung allograft dysfunction and the role of redo transplantation [PDF]

JHLT Open
Background: Lung transplantation (LTx) is a treatment option for end-stage lung disease. Chronic lung allograft dysfunction (CLAD) poses challenges to long-term survival.
Zsofia Kovacs, Jens Gottlieb, Susanne Simon, Alberto Benazzo, Peter Jaksch   +4 more
doaj   +2 more sources