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Restrictive allograft syndrome after lung transplantation: new radiological insights
To describe the CT changes in patients with restrictive allograft syndrome (RAS) after lung transplantation, before and after clinical diagnosis.This retrospective study included 22 patients with clinical diagnosis of RAS. Diagnosis was based on a combination of forced expiratory volume (FEV1) decline (≥20 %) and total lung capacity (TLC) decline (≥10 %
Adriana Dubbeldam +7 more
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Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome
Transplantation, 2013Chronic rejection is the major problem hampering long-term survival after lung transplantation. Recently, it became clear that patients may develop an obstructive (bronchiolitis obliterans syndrome [BOS]) or a restrictive lung function defect (restrictive allograft syndrome [RAS]), for which specific risk factors are unknown.A retrospective analysis of
Stijn E, Verleden +8 more
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Restrictive allograft syndrome (RAS): A novel form of chronic lung allograft dysfunction
The Journal of Heart and Lung Transplantation, 2011Bronchiolitis obliterans syndrome (BOS) with small-airway pathology and obstructive pulmonary physiology may not be the only form of chronic lung allograft dysfunction (CLAD) after lung transplantation. Characteristics of a form of CLAD consisting of restrictive functional changes involving peripheral lung pathology were investigated.Patients who ...
Masaaki, Sato +10 more
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08.02 - Transplantation, 2022
Introduction: Restrictive Chronic lung Allograft dysfunction (RAS) is a serious complication following lung transplantation (LTx) defined by restrictive decline in lung function and progressive fibrosis of the allograft, affecting both morbidity and mortality.
Schultz, H H +5 more
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Introduction: Restrictive Chronic lung Allograft dysfunction (RAS) is a serious complication following lung transplantation (LTx) defined by restrictive decline in lung function and progressive fibrosis of the allograft, affecting both morbidity and mortality.
Schultz, H H +5 more
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Clinical predictors for restrictive allograft syndrome: A nested case-control study
Risk factors for restrictive allograft syndrome (RAS), a severe phenotype of chronic lung allograft dysfunction (CLAD) after lung transplantation, are currently not well known. In this retrospective nested case-control-study, we analyzed 69 patients with RAS and 69 matched non-CLAD controls to identify clinical risk factors for RAS.
Hanne Beeckmans +24 more
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Cytotoxic T Cells Early after Lung Transplantation Precede the Restrictive Allograft Syndrome
Purpose The outcome after lung transplantation is limited by chronic lung allograft dysfunction (CLAD), subclassified into bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). RAS tends to an earlier, more severe and more rapid course as compared to BOS.
Tomoyuki Nakagiri +10 more
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Diagnosis of Restrictive Allograft Syndrome (RAS) without Using Total Lung Capacity
Purpose RAS is a form of chronic lung allograft dysfunction (CLAD) distinct from bronchiolitis obliterans syndrome (BOS). The major limitation of the original diagnostic criteria depending on total lung capacity (TLC) is the need for plethysmography rather than simple spirometry. We intended to seek for the use of spirometry in the diagnosis of RAS.
Masaaki Sato +4 more
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Nintedanib as Bridge Therapy to Retransplantation for Restrictive Allograft Syndrome: A Case Report
Sergio Ghirardo +3 more
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