Results 11 to 20 of about 2,233 (156)
Restrictive Allograft Syndrome After COVID-19 Pneumonia: A Case Report. [PDF]
CureusChronic lung allograft dysfunction (CLAD) continues to be the leading cause of death in the long term after lung transplantation (LTx). CLAD has the following two main subtypes: bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS).
Ohizumi Y +5 more
europepmc +5 more sources
Pirfenidone: A Potential New Therapy for Restrictive Allograft Syndrome? [PDF]
American Journal of Transplantation, 2013 This case report describes the evolution of pulmonary function findings (FVC, FEV1 and TLC) and CT features with pirfenidone treatment for restrictive allograft syndrome following lung transplantation. Furthermore, we herein report hypermetabolic activity on (18) F-FDG PET imaging in this setting, which could indicate active fibroproliferation and ...
Robin Vos +11 more
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Current Opinion in Organ Transplantation, 2022 Purpose of review New chronic lung allograft dysfunction (CLAD) consensus documents were published in 2019, defining four phenotypes; bronchiolitis obliterans syndrome, restrictive allograft syndrome, mixed and undefined. Clearly, validation of these guidelines in a real life cohort is critical.
Geert M. Verleden +3 more
openalex +5 more sources
Progression pattern of restrictive allograft syndrome after lung transplantation [PDF]
The Journal of Heart and Lung Transplantation, 2012 Restrictive allograft syndrome (RAS) is a novel form of chronic lung allograft dysfunction after lung transplantation. RAS is characterized by restrictive physiology and peripheral lung fibrosis. The purpose of the study is to analyze progression patterns of RAS.Clinical information, pulmonary function test results and radiographic findings were ...
Masaaki Sato +4 more
openalex +3 more sources
Neutrophilic Reversible Allograft Dysfunction (NRAD) and Restrictive Allograft Syndrome (RAS) [PDF]
Seminars in Respiratory and Critical Care Medicine, 2013 Lung transplantation is currently considered as an ultimate live-saving treatment for selected patients suffering from end-stage pulmonary disease. Long-term survival, however, is hampered by chronic rejection, or chronic lung allograft dysfunction (CLAD).
Stijn E. Verleden +8 more
openalex +4 more sources
The Journal of Heart and Lung Transplantation, 2021 Chronic lung allograft dysfunction in lung transplant recipients (LTxRs) has 2 phenotypes: obstructive bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). Our goal was to define distinct immunologic markers of exosomes from LTxRs with BOS or RAS.Plasma was collected from LTxRs with BOS (n = 18), RAS (n = 13), and from ...
Sandhya Bansal +7 more
openalex +4 more sources
The accuracy of forced vital capacity for diagnosing restrictive allograft syndrome and mixed phenotype of chronic lung allograft dysfunction [PDF]
European Respiratory Journal, 2021 Lung transplantation has become an invaluable approach for the treatment of end-stage respiratory diseases. However, survival after lung transplant remains limited due to chronic lung allograft dysfunction (CLAD), a fibrotic process affecting the airway and/or parenchymal compartments of the lung graft leading to a significant and persistent ...
Liran Levy +13 more
openalex +3 more sources
Restrictive allograft syndrome post lung transplantation is characterized by pleuroparenchymal fibroelastosis [PDF]
Modern Pathology, 2012 We previously described restrictive allograft syndrome as a form of chronic lung allograft dysfunction, demonstrating restrictive pulmonary function decline. However, the histopathological correlates of restrictive allograft syndrome have yet to be satisfactorily described.
Efrat Ofek +10 more
openalex +3 more sources
Pirfenidone in restrictive allograft syndrome after lung transplantation: A case series [PDF]
American Journal of Transplantation, 2018 Pirfenidone may attenuate the decline of pulmonary function in restrictive allograft syndrome (RAS) after lung transplantation. We retrospectively assessed all lung transplant recipients with RAS who were treated with pirfenidone for at least 3 months (n = 11) in our lung transplant center and report on their long-term outcomes following initiation of ...
Robin Vos +17 more
openalex +3 more sources
Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome―A consensus report from the Pulmonary Council of the ISHLT [PDF]
The Journal of Heart and Lung Transplantation, 2019 n ...
Allan R. Glanville +17 more
openalex +6 more sources