Results 161 to 170 of about 616,172 (304)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Health impact of the first and second wave of COVID-19 and related restrictive measures among nursing home residents: a scoping review. [PDF]

open access: yesBMC Health Serv Res, 2022
Verbiest MEA   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Disentangling Market Access Effects for ASEAN Members under an ASEAN-EU FTA [PDF]

open access: yes
The paper develops two synthetic measures at the HS-10 level to depict effective market access for a country receiving preferential access and applies these to the market access ASEAN members would receive on impact following the implementation of an FTA
Bolormaa Tumurchudur   +2 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Community feedbacks on COVID-19 restrictive measures and health risk management decolonization perspectives: a socio-anthropological study

open access: yes, 2023
Genda E   +7 more
europepmc   +1 more source

Impact of the COVID-19 pandemic and restrictive measures on acute appendicitis: Do not let your guard down.

open access: yesJ Minim Access Surg, 2022
Herrera JJ   +5 more
europepmc   +1 more source

The psychological impact of COVID-19 and restrictive measures in the world. [PDF]

open access: yesJ Affect Disord, 2021
Passavanti M   +11 more
europepmc   +1 more source

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