Results 111 to 120 of about 255,114 (264)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Political Restructuring in Nigeria: The Need, Challenges and Prospects

open access: yes, 2018
Restructuring is a song on the lips of many Nigerians It has trended for decades and seems to be an inter-generational topical issue in Nigeria The persistent call for restructuring takes numerous dimensions but particularly outstanding is in the ...
Ideobodo Nwafor-Orizu   +2 more
core  

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Inequality and identity in contemporary processes of labour market restructuring [PDF]

open access: yes, 2007
Contemporary processes of labour market restructuring have resulted in increasing social and spacial inequalities in the United Kingdom. While the well discussed-issues of class, race and gender continue to be correlated to inequality, the decline in ...
Forsyth, A.
core   +1 more source

Restructuring and Business Reengineering in Integrative Processes [PDF]

open access: yes
Globalisation has intensified competition to such an extent that the corporations, merely with one’s own resources, cannot achieve acceptable success any longer. Objectives, which had been set-up prior to establishing the alliance in order to justify the
Drago Dubrovski
core  

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Electricity Restructuring and Regulation in the Provinces: Ontario and Beyond [PDF]

open access: yes
Competitive electricity markets are artificial markets with extensive rules for all participants arising from the complex interconnections of the electricity network.
Donald N. Dewees
core  

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

open access: yesAdvanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu   +7 more
wiley   +1 more source

Future gender relations in global restructuring processes case study evidence from knowledge-intensive, manufacturing and service occupations [PDF]

open access: yes
Global restructuring processes have not only strong implications for European working and living realities, but also have specific outcomes with regard to gender relations.
Linda Nierling
core  

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