Results 101 to 110 of about 6,225 (309)

Animacy and Affectedness in Germanic Languages

Open Linguistics, 2018
This paper deals with the influence of animacy on affectedness. German, like other Germanic languages, requires oblique marking of the inanimate undergoer argument of verbs of contact by impact (e.g.
Fleischhauer Jens
doaj   +1 more source

Affordances perspective and grammaticalization: Incorporation of language, environment and users in the model of semantic paths [PDF]

, 2015
The present paper demonstrates that insights from the affordances perspective can contribute to developing a more comprehensive model of grammaticalization.
Andrason, Alexander, Visser, Marianna
core   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Az adverbiumok mondattani és jelentéstani kérdései = The syntax and syntax-semantics interface of adverbial modification [PDF]

, 2009
A határozószók és a határozók alaktani, mondattani és funkcionális kérdéseit vizsgáltuk a generatív nyelvelmélet keretében, főként magyar anyag alapján.
Bartos, Huba, Bende Farkas, Ágnes, Egedi, Barbara, Kovács, András, Kováts, Zsófia, Márkus, Andrea, Peredy, Márta Dóra, Pál, Alexandra, Surányi, Balázs, É. Kiss, Katalin, Ürögdi, Barbara   +10 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Counterfactuals and the loss of BE in the history of English [PDF]

, 2008
In the course of the ME period, HAVE began to encroach on territory previously held by BE. According to Rydén and Brorström (1987); Kytö (1997), this occurred especially in iterative and durational contexts, in the perfect infinitive and modal ...
Alexiadou, Artemis, McFadden, Thomas
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Lexical classes and constructions: an analysis of the constructional realization of entity-specific change-of-state English verbs

ExELL (Explorations in English Language and Linguistics)
This study analyzes a so far neglected part of the constructional behavior of Levin’s (1993) entity-specific change-of-state verbs. More specifically, we discuss the integration of verbs from this lexical class into the intransitive-resultative ...
Francisco José Ruiz de Mendoza Ibáñez, Andreea Rosca   +1 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source