Development of SNP Set for the Marker-Assisted Selection of Guar (Cyamopsis tetragonoloba (L.) Taub.) Based on a Custom Reference Genome Assembly. [PDF]
Plants (Basel), 2021 Grigoreva E +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Influences of Language Functions on Linguistic Features: Multi-Dimensional and Entropy Analyses of Academic and Entertainment Registers. [PDF]
Entropy (Basel)Hu C, Zhu Y, Yuan L.
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Treatment decision making in psychiatry: Formulating patients' perspectives in outpatient psychiatric consultations. [PDF]
Front Psychol, 2023 Yao X, Zhang X.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Zhuang-Mandarin bilingual children in rural China and the role of grandparental input in early bilingualism. [PDF]
PLoS OneMai Z +6 more
europepmc +1 more source
Data on the use of optional ergative case marking in Tujia, an endangered language of southwest China. [PDF]
Data Brief, 2019 Lu M, van de Weijer J, Ma Y, Liu Z.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A Conceptual Restructuring of Spatial Motion Expressions in Chinese L2. [PDF]
Front Psychol, 2018 Sparvoli C.
europepmc +1 more source