Results 51 to 60 of about 82,287 (251)

Use of neuromuscular blocking agents in obstetric anesthesiology: a comprehensive literature review [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ)
The use of neuromuscular blocking agents (NMBAs) in obstetric anesthesiology plays a pivotal role in airway management during surgical interventions, particularly cesarean section under general anesthesia.
C. Pellegrino, S. Sorrenti, M. Ciuffreda, E. Pisello, L. Brugiaferri, C. Piangatelli, D. Galante   +6 more
doaj   +1 more source

Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning

Scientific Reports, 2022
Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths.
Sarah Piel, Joanna I. Janowska, J. Laurenson Ward, Meagan J. McManus, Joshua S. Jose, Jonathan Starr, Malkah Sheldon, Carly L. Clayman, Eskil Elmér, Magnus J. Hansson, David H. Jang, Michael Karlsson, Johannes K. Ehinger, Todd J. Kilbaugh   +13 more
doaj   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

Predictive study of pharmacological reversal for residual neuromuscular blockade and postoperative pulmonary complications: a prospective, observational, cohort study

Scientific Reports, 2022
In recent years, some studies have generated controversy since they conclude that intraoperatively pharmacological reversal of neuromuscular blockade does not contribute to the reduction of postoperative residual neuromuscular blockade or pulmonary ...
Cristian Aragón-Benedí, Ana Pascual-Bellosta, Sonia Ortega-Lucea, Sara Visiedo-Sánchez, Javier Martínez-Ubieto, Research Group in Anaesthesia, Resuscitation, and Perioperative Medicine of Institute for Health Research Aragón (ISS Aragón)   +5 more
doaj   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Radical Resection of the Third Portion of the Duodenum for Secondary Aortoduodenal Fistula

Annals of Gastroenterological Surgery, EarlyView.
Secondary aortoduodenal fistula most commonly involves the third portion of the duodenum and requires definitive management of both vascular and gastrointestinal components. We demonstrate a step‐by‐step technique for radical duodenal resection and reconstruction performed in structured collaboration with cardiovascular surgeons.
Koji Kubota, Akira Shimizu, Tsuyoshi Notake, Tatsuichiro Seto, Yuji Soejima   +4 more
wiley   +1 more source

European Resuscitation Council Guidelines 2025 Executive Summary

: The 2025 European Resuscitation Council (ERC) Guidelines present the most up-to-date evidence-based guidelines for the practice of resuscitation across Europe.
Spartinou, Anastasia, Monnelly, Vix, Baldi, Enrico, Semeraro, Federico, Djakow, Jana, Karageorgos, Vlasios, Lott, Carsten, Nabecker, Sabine, Ek, Jacqueline Eleonora, de Raad, Timo, Nolan, Jerry P., Olasveengen, Theresa M., Perkins, Gavin D., Rogers, Jessica, Sandroni, Claudio, Biarent, Dominique, Monsieurs, Koenraad G., Djarv, Therese, van Gils, Marlie, Yeung, Joyce, Lauridsen, Kasper G., Soar, Jasmeet, Raffay, Violetta, Smyth, Michael A., Madar, John, Schnaubelt, Sebastian, Greif, Robert, von Goor, Sander, Grasner, Jan-Thorsten, Hogeveen, Marije, Wittig, Johannes, Nikolaou, Nikolaos   +31 more
core   +2 more sources

Improving the Quality of Postoperative Recovery of Elderly and Senile Patients with Circulatory Insuficiency

Perioperative Medicine
A comparison of prolonged epidural analgesia (PEA) with conventional on-demand analgesia in geriatric patients with circulatory insuffi ciency (CI) who underwent surgery on the lower extremities demonstrated a pronounced opioid-sparing effect in them in
Z Gaziev, O Sayitov, Sh Valiev, M Shorustamov   +3 more
doaj   +1 more source

Integrating Reinforcement Learning With Explainable Artificial Intelligence for Real‐Time Clinical Decision Support in Dynamic Healthcare Environments

Advanced Intelligent Systems, EarlyView.
A hybrid Reinforcement Learning–Explainable AI framework integrates SHAP and LIME explanations directly into a Deep Q‐Network inference loop for real‐time ICU decision support. Trained on 18 142 mechanically ventilated stays from the eICU database, the system attains 93.0% decision accuracy, 20% fewer errors than RL alone, and a 91% clinician trust ...
Jannatul Ferdaus Disha, MD Faiaz Zaman Dehan, Kazi Md. Tanvir Anzum   +2 more
wiley   +1 more source

High-flow nasal oxygen versus face-mask ventilation for rapid sequence induction in non-elective surgical patients: a randomized controlled trial

BMC Anesthesiology
Background Patients undergoing non-elective surgery frequently require rapid sequence induction (RSI) because of concerns related to recent oral intake, impaired gastric emptying, or uncertain fasting status.
Nguyen Duc Lam, Le Dinh Thanh Son, Tran Minh Phat, Nguyen Dang Thu, Nguyen Thuy Nga, Vuong Trung Son, Bui Minh Hong   +6 more
doaj   +1 more source