Results 71 to 80 of about 171,759 (265)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Effects of the timing of administration of IgM- and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of septic shock patients

Annals of Intensive Care, 2018
Background The administration of endovenous immunoglobulins in patients with septic shock could be beneficial and preparations enriched with IgA and IgM (ivIgGAM) seem to be more effective than those containing only IgG. In a previous study Berlot et al.
Giorgio Berlot, Michele Claudio Vassallo, Nicola Busetto, Margarita Nieto Yabar, Tatiana Istrati, Silvia Baronio, Giada Quarantotto, Mattia Bixio, Giulia Barbati, Roberto Dattola, Irene Longo, Antonino Chillemi, Alice Scamperle, Fulvio Iscra, Ariella Tomasini   +14 more
doaj   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Effect of dimethyl fumarate on mitochondrial metabolism in a pediatric porcine model of asphyxia-induced in-hospital cardiac arrest

Scientific Reports
Neurological and cardiac injuries are significant contributors to morbidity and mortality following pediatric in-hospital cardiac arrest (IHCA). Preservation of mitochondrial function may be critical for reducing these injuries.
Sarah Piel, Meagan J. McManus, Kristina N. Heye, Forrest Beaulieu, Hossein Fazelinia, Joanna I. Janowska, Bryce MacTurk, Jonathan Starr, Hunter Gaudio, Nisha Patel, Marco M. Hefti, Martin E. Smalley, Jordan N. Hook, Neha V. Kohli, James Bruton, Thomas Hallowell, Nile Delso, Anna Roberts, Yuxi Lin, Johannes K. Ehinger, Michael Karlsson, Robert A. Berg, Ryan W. Morgan, Todd J. Kilbaugh   +23 more
doaj   +1 more source

Nutrition in patients with traumatic brain injury: Nutrition in patients with TBI [PDF]

Serbian Journal of Anesthesia and Intensive Therapy
Traumatic brain injury (TBI) is a condition with a high morbidity and mortality rate. From a medical point of view, little can be done to prevent primary brain injuries.
Stojanović Milena, Janković Radmilo, Ranđelović Milica, Vasilijić Milena, Nikolić Aleksandar, Radeka Jovan   +5 more
doaj   +1 more source

‘They Should Understand That the Anorexia Drives me to do Anything’: Exploring How Individuals With Anorexia Nervosa Make Sense of the Experience of Medical Admissions

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a complex disorder associated with significant morbidity and mortality. Some people with AN require medical admissions to manage physical complications. Currently, little is known about how these medical admissions are experienced, despite an increase in the number of individuals being hospitalised.
Hannah Webb, Penny Neild, Vanessa Lawrence, Ulrike Schmidt, Maria Griffiths   +4 more
wiley   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

How to predict neurogenic pulmonary edema in aneurysmal subarachnoid hemorrhage?: Neurogenic pulmonary edema in aneurysmal SAH [PDF]

Serbian Journal of Anesthesia and Intensive Therapy, 2019
Introduction: Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema after sudden raise of intracranial pressure.
Nastasović Tijana, Milaković Branko, Stošić Mila, Lazarević Ivana, Kaluđerović Miloš, Grujičić Danica   +5 more
doaj  

Pulsed Light Technology in Food Safety and Preservation: Principles, Applications, and Future Directions

Food Chemistry International, EarlyView.
Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad, Laiba Younas, Fatima Javed, Rimsha Amjad, Muhammad Tayyab Raza   +4 more
wiley   +1 more source

ICU Admission-Related Factors Affecting the Duration of Mechanical Ventilation After Elective Cardiac Surgery—Retrospective Cohort Study from a Tertiary Center in Croatia

Medicina
Background and Objectives: Enhancing recovery after cardiac surgery involves minimally invasive procedures, early extubation/mobilization, and swift discharge. While mechanical ventilation is often essential post-operation, prolonged invasive ventilation
Darko Kristović, Verica Mikecin, Ivana Presečki, Zrinka Šafarić Oremuš, Nataša Sojčić, Ivan Gospić, Hrvoje Lasić, Sanja Sakan, Danijela Kralj Husajna, Nikola Bradić, Jasminka Peršec, Andrej Šribar   +11 more
doaj   +1 more source