Results 81 to 90 of about 177,689 (265)
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare +7 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate the effects of aortic occlusion (AO) on severe postpartum hemorrhage (PPH)—a leading cause of preventable maternal mortality—using a nationwide maternal death registry in Japan. Methods A nationwide retrospective observational study of hemorrhage‐related maternal deaths was conducted in Japan between 2010 and 2024 ...
Makoto Aoki +18 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background Approximately one in four first‐time mothers reach the second stage of labor but cannot have a spontaneous vaginal birth, necessitating an intervention such as forceps to facilitate birth. Objective This study synthesizes evidence comparing severe maternal morbidity (SMM) and neonatal morbidity or mortality (SNMM) following forceps ...
Irina I. Oltean +2 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective The body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) of the mother before pregnancy and the growth of weight during pregnancy are both important perinatal health determinants. The aim of the present study was to examine the association between the maternal BMI and obstetric and ...
Randa Elsayed +7 more
wiley +1 more source
Fetal growth trajectories and neonatal outcomes: A French population‐based study
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective This study assesses whether fetal growth trajectories are associated with neonatal outcomes. Methods The study population included 8537 singleton liveborn infants from the 2021 French National Perinatal Survey. Fetal growth trajectories were assessed between second and third trimester routine ultrasounds and between the third ...
Pierre Gibert +22 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer +20 more
wiley +1 more source
Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia
iMeta, EarlyView.Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen +23 more
wiley +1 more source
Resuscitating resuscitation science in TRANSFUSION [PDF]
Transfusion, 2017 John R. Hess +2 more
openaire +2 more sources