Results 51 to 60 of about 395,110 (339)
C-Jun N-terminal kinase 2 promotes liver injury via the mitochondrial permeability transition after hemorrhage and resuscitation [PDF]
, 2012 Hemorrhagic shock leads to hepatic hypoperfusion and activation of mitogen-activated stress kinases (MAPK) like c-Jun N-terminal kinase (JNK) 1 and 2. Our aim was to determine whether mitochondrial dysfunction leading to hepatic necrosis and apoptosis ...
Czerny, Christoph +6 more
core +2 more sources
Advanced Science, EarlyView.The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu +17 more
wiley +1 more source
Nurses\u27 Perception of Family Presence During Resuscitation [PDF]
, 2005 Background Family witnessed resuscitation (FWR) is the concept of allowing family members at bedside during cardiopulmonary resuscitation. Studies have shown that the lack of standard policies by hospitals regarding FWR forces nurses to make different ...
Njoku, Josephine
core +1 more source
Intraosseous vascular access in critically ill adults-a review of the literature [PDF]
, 2015 Aim & objectives. This literature review aim is to present a detailed investigation critiquing contemporary practices of intraosseous vascular access in adult patients.
Garside, Joanne +2 more
core +1 more source
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Advanced Science, EarlyView.Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Use of neuromuscular blocking agents in obstetric anesthesiology: a comprehensive literature review [PDF]
Pediatric Anesthesia and Critical Care Journal (PACCJ)The use of neuromuscular blocking agents (NMBAs) in obstetric anesthesiology plays a pivotal role in airway management during surgical interventions, particularly cesarean section under general anesthesia.
C. Pellegrino +6 more
doaj +1 more source
Chromatic‐Zone Mapping for Rapid Discovery of Antibacterial Alloys with Nanostructured Surfaces
Advanced Science, EarlyView.A high‐throughput parallel chromatic‐zone screening strategy that enables the simultaneous screening of alloy composition and surface structure. Ultimately linking surface color, composition, and morphology with antimicrobial performance enables the screening and prediction of color zones, thereby reducing characterization requirements by 90% and ...
Qiu‐Yu Zhao +8 more
wiley +1 more source
Proposal of a management algorithm for delayed neurological syndrome following carbon monoxide poisoning. [PDF]
Pediatric Anesthesia and Critical Care Journal (PACCJ)Delayed encephalopathy or post-interval syndrome can develop some time after acute carbon monoxide (CO) poisoning and its hyperbaric treatment. The clinical presentation is highly heterogeneous and variable, and this syndrome is often underdiagnosed ...
M. Ciuffreda +7 more
doaj +1 more source
Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation [PDF]
, 2021 Tiffany S. Ko +17 more
openalex +1 more source
Advanced Science, EarlyView.Helical nanostructures co‐assembled from berberine (BBR) and Fmoc‐Y display supramolecular‐chirality‐dependent photodynamic antibacterial activity. The molecular chirality of Fmoc‐Y organizes achiral BBR into chiral nanofibers, where supramolecular handedness controls bacterial surface adsorption, membrane penetration, intracellular BBR delivery, and ...
Haoqiang Zhao +9 more
wiley +1 more source