Results 51 to 60 of about 223,393 (295)

Dexmedetomidine for transcatheter aortic valve implantation. Does it protect against acute kidney injury? [PDF]

open access: yesRevista Chilena de Anestesia, 2023
Guerrero Orriach J.L.   +5 more
doaj   +1 more source

NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer

open access: yesAdvanced Science, EarlyView.
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen   +8 more
wiley   +1 more source

Proposal of a management algorithm for delayed neurological syndrome following carbon monoxide poisoning. [PDF]

open access: yesPediatric Anesthesia and Critical Care Journal (PACCJ)
Delayed encephalopathy or post-interval syndrome can develop some time after acute carbon monoxide (CO) poisoning and its hyperbaric treatment. The clinical presentation is highly heterogeneous and variable, and this syndrome is often underdiagnosed ...
M. Ciuffreda   +7 more
doaj   +1 more source

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

open access: yesAdvanced Science, EarlyView.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang   +11 more
wiley   +1 more source

Hypotensive Resuscitation [PDF]

open access: yesCurrent Anesthesiology Reports, 2014
Hypotensive resuscitation is a component of damage control resuscitation, the evolving approach to resuscitation in severely injured trauma patients. Resuscitation strategies used in treating severely injured trauma patients have changed dramatically over the last 20 years.
Jeremy B, Smith   +2 more
openaire   +2 more sources

TGM2 Aggravates Acute Pancreatitis by Impairing Macrophage Efferocytosis Through Inhibition of the STAT6–GAS6 Axis

open access: yesAdvanced Science, EarlyView.
This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu   +8 more
wiley   +1 more source

Correction to: Effects of the timing of administration of IgM- and IgA-enriched intravenous polyclonal immunoglobulins on the outcome of septic shock patients

open access: yesAnnals of Intensive Care, 2019
Following publication of the original article [1], we have been notified that the tagging of the author name was done incorrectly in the XML version of the paper. The correct given name is Michele Claudio, and the family name is Vassallo.
Giorgio Berlot   +14 more
doaj   +1 more source

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

open access: yesAdvanced Science, EarlyView.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao   +8 more
wiley   +1 more source

Improving the Quality of Postoperative Recovery of Elderly and Senile Patients with Circulatory Insuficiency

open access: yesPerioperative Medicine
A comparison of prolonged epidural analgesia (PEA) with conventional on-demand analgesia in geriatric patients with circulatory insuffi ciency (CI) who underwent surgery on the lower extremities demonstrated a pronounced opioid-sparing effect in them in
Z Gaziev   +3 more
doaj   +1 more source

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