Results 81 to 90 of about 223,393 (295)

Effect of dimethyl fumarate on mitochondrial metabolism in a pediatric porcine model of asphyxia-induced in-hospital cardiac arrest

Scientific Reports
Neurological and cardiac injuries are significant contributors to morbidity and mortality following pediatric in-hospital cardiac arrest (IHCA). Preservation of mitochondrial function may be critical for reducing these injuries.
Sarah Piel, Meagan J. McManus, Kristina N. Heye, Forrest Beaulieu, Hossein Fazelinia, Joanna I. Janowska, Bryce MacTurk, Jonathan Starr, Hunter Gaudio, Nisha Patel, Marco M. Hefti, Martin E. Smalley, Jordan N. Hook, Neha V. Kohli, James Bruton, Thomas Hallowell, Nile Delso, Anna Roberts, Yuxi Lin, Johannes K. Ehinger, Michael Karlsson, Robert A. Berg, Ryan W. Morgan, Todd J. Kilbaugh   +23 more
doaj   +1 more source

TAVR in Male Patients With Large Aortic Valve Annuli: A Propensity‐Matched Analysis of Balloon‐Expandable Versus Self‐Expanding Valves

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Trans‐catheter aortic valve replacement (TAVR) in patients with large annuli poses procedural difficulties and possible complications. Aims We sought to compare the peri‐procedural and long‐term outcomes of patients with large annuli undergoing TAVR with self‐expanding (SEV) versus balloon‐expandable (BEV) valves.
Lior Zornitzki, Itamar Loewenstein, Shir Frydman, Maayan Konigstein, Jeremy Ben‐Shoshan, Yaron Arbel, Israel Barbash, Ran Kornowski, Gabby G. Elbaz, Danny Dvir, Ariel Finkelstein, Shmuel Banai, Arie Steinvil   +12 more
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Pediatric poisonings: analysis and clinical management. [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ)
Pediatric poisonings represent a significant global health issue, with important implications for children’s well-be- ing and healthcare resources. Toxic agents include drugs, household products, plants and substances of abuse, with exposure occurring ...
M. Cirronis, G. Eleftheriou, M. Ciuffreda, A. Monacelli, S. Sorrenti, E. Pisello, G. Ledda, C. Piangatelli, D. Galante   +8 more
doaj   +1 more source

Clinical Impact of Angiographic Complications Occurring During Percutaneous Coronary Interventions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The clinical impact of different types of angiographic complications during elective PCIs remains largely unexplored. Aims To explore the incidence, management, and outcomes of angiographic complications by type and severity during non‐urgent, non‐CTO PCIs. Methods Clinical and procedural characteristics were prospectively collected
Emiliano Bianchini, Mattia Lunardi, Fabio Casamassima, Francesco Bianchini, Mattia Basile, Enrico Romagnoli, Cristina Aurigemma, Lazzaro Paraggio, Francesco Fracassi, Rocco Antonio Montone, Antonino Buffon, Luigi Cappannoli, Carolina Ierardi, Tommaso Sanna, Antonio Maria Leone, Carlo Trani, Francesco Burzotta   +16 more
wiley   +1 more source

How to predict neurogenic pulmonary edema in aneurysmal subarachnoid hemorrhage?: Neurogenic pulmonary edema in aneurysmal SAH [PDF]

Serbian Journal of Anesthesia and Intensive Therapy, 2019
Introduction: Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema after sudden raise of intracranial pressure.
Nastasović Tijana, Milaković Branko, Stošić Mila, Lazarević Ivana, Kaluđerović Miloš, Grujičić Danica   +5 more
doaj  

Long‐Term Impact of Prosthesis‐Patient Mismatch After Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annuli

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Prosthesis‐patient mismatch (PPM) remains common following transcatheter aortic valve replacement (TAVR) and is associated with worse clinical outcomes. PPM is of particular concern in small aortic annuli (SAA). Aims To compare the incidence, predictors, and long‐term impact of PPM in SAA TAVR.
Itamar Loewenstein, Bar Gitter, Tamar Itach, Yaron Arbel, Jeremy Ben‐Shoshan, Maayan Konigstein, Ariel Finkelstein, Amir Halkin, Shmuel Banai, Arie Steinvil   +9 more
wiley   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source