Results 61 to 70 of about 837,121 (281)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
BuildingsIn urban redevelopment, adding basements beneath existing buildings often requires specialized retaining structures, such as existing and newly added double-row piles, yet their complex load-sharing mechanism is not yet fully understood.
Yiming Jin +3 more
doaj +1 more source
Mechanical Behavior and Failure Analysis of Prosthetic Retaining Screws after Long‐term Use In Vivo. Part 1: Characterization of Adhesive Wear and Structure of Retaining Screws [PDF]
, 2007 Purpose: The general aim of this study and those presented in Parts 2–4 of this series was to characterize the structure, properties, wear, and fracture of prosthetic retaining screws in fixed detachable hybrid prostheses after long‐term use in vivo ...
Al Jabbari, Youssef S. +4 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
BuildingsThe precise calculation and effective control of the horizontal displacement of deep foundation pit retaining structures are critical for foundation pit support design and construction.
Jianghong Zhu, Feng Qian, Jianping Cai
doaj +1 more source
Timber sheet pile-vegetation model for stream bank retaining structure [PDF]
E3S Web of Conferences, 2019 Timber sheet piles are widely used to protect canal and stream banks. Quite often, riparian vegetation also grows along these retaining structures. Roots of riparian vegetation mechanically reinforce the soil with their root systems.
Kamath Abhijith +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
INTERACTION OF SOIL-CEMENT PILE SUPPORTING STRUCTURES WITH THE BODY OF A LANDSLIDE
Nauka ta progres transportu, 2017 Purpose. Analysis and comparison of the landslide slope finite element model calculation results of the appliance of soil-cement piles, depending on the variation of the retaining structure rigidity, makes it possible to evaluate the effectiveness of ...
D. Y. Ihnatenko +2 more
doaj +1 more source
Advances in Civil Engineering, 2022 In recent years, with the continuous advancement of urbanization in China and the gradual increase in the utilization scale of underground space, foundation pits may build in a narrow and compact environment.
Wenfeng Liu +3 more
doaj +1 more source
Modeling the Role of the Cell Cycle in Regulating Proteus mirabilis Swarm-Colony Development
, 2005 We present models and computational results which indicate that the spatial and temporal regularity seen in Proteus mirabilis swarm-colony development is largely an expression of a sharp age of dedifferentiation in the cell cycle from motile swarmer ...
Ayati +11 more
core +1 more source