Results 31 to 40 of about 1,139,074 (289)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Calculation and analysis of earth pressure under limited displacement considering influences of internal friction angle

open access: yesYantu gongcheng xuebao, 2021
Taking the retaining wall in cohesive and cohesionless backfills as the research object, based on the existing results, a formula for calculating the earth pressure under the limited displacement considering the influences of internal friction angle is ...
ZHANG Le 1, DANG Fa-ning 1, WANG Xu 1, DING Jiu-long 1, GAO Jun 1
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Application of elastic cable theory in design of reinforced earth structure

open access: yesYantu gongcheng xuebao, 2018
Under differential settlement, the researches on the joint stress between the reinforced earth retaining wall panel and the reinforced materials and the deformation of the reinforced materials at the present stage are few.
WANG Zong-jian 1,2, MA Shu-wen 2, TANG Xiao-shuang 2, WU Jin-ming 2, ZHI Xian-ping 1, LU Liang 1
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ground movements due to excavation in clay: physical and analytical models [PDF]

open access: yes, 2010
In view of the recent catastrophes associated with deep excavations, there is an urgent need to provide vital guidelines on the design of the construction process.

core   +2 more sources

Field tests on retaining wall constructed with soilbags filled with clayey soils

open access: yesYantu gongcheng xuebao, 2018
In the construction of approach channels in a plain area, a lot of clayey soils are excavated. If the excavated clayey soils are filled into woven bags, they can be used to build retaining walls.
FAN Ke-wei 1, LIU Si-hong 1, XU Si-yuan 1, WANG Jian-lei 1,2
doaj   +1 more source

Numerical Investigation of Impact Characteristics of Rigid Retaining Wall for Blocking Landslides: A Case Study of the Shum Wan Road Landslide

open access: yesGeofluids, 2022
Landslides pose a serious threat to the downstream infrastructure and personnel safety. For situations where the location of possible landslides is difficult to determine, or the potential landslides areas are widely distributed and scattered, passive ...
Yunyun Fan   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Performance of a propped retaining wall at the CTRL, Ashford

open access: yes, 2006
This thesis is based on the field monitoring of a propped bored pile retaining wall installedin an overconsolidated clay. Pile bending moments, prop loads, pore water pressures andlateral earth pressures were logged automatically at intervals of up to 5 ...
Clark, Jo
core   +1 more source

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