Results 101 to 110 of about 2,838,074 (304)

Is grade retention the solution for failing? [PDF]

open access: yes, 2020
The convenience of grade retention for students’ adequate progression in the education system has been the focus of great debate. However, the characteristics that the grade retention variable presents when explaining students’ academic achievement has ...
López Agudo, Luis Alejandro   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Alaska’s Judicial Retention Elections: A Comparative Analysis [PDF]

open access: yes, 2017
The results of recent judicial retention elections in Alaska, and the recent increase in political activities related to judicial selection in Alaska and many other states, have given rise to concerns about the fates of future Alaska retention candidates.
Klumpp, Albert J.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Impact of changing pre‐exposure prophylaxis regimens on retention among men who have sex with men in Hanoi, Vietnam (2020−2023): a cohort study

open access: yesJournal of the International AIDS Society
Introduction We examined the association of pre‐exposure prophylaxis (PrEP) programme retention with the use of daily, event‐driven (ED) or regimen switching reported during follow‐up at any point prior to discontinuation among men who have sex with men (
Naira Setrakian   +5 more
doaj   +1 more source

Dichloroaniline retention by nanofiltration membranes [PDF]

open access: yes, 2005
This study evaluates the performance of two nanofiltration membranes in removing a herbicide: dichloroaniline. The membranes, one polyamide and one cellulose acetate, have a cut-off in the range 150–300 g/mol (manufacturers’ data). The experiments were
Aimar, Pierre   +3 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Leadership Practices That Enable and Constrain Retention in Early Childhood Education and Care Settings in Australia

open access: yesEducation Sciences
Australia’s early childhood education and care (ECEC) sector is in crisis, with educator job tenure decreasing and workforce supply threatened. Despite worsening retention rates, many highly skilled educators remain and thrive within ECEC settings ...
Suzanne Garrett, Leanne Gibbs
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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