Results 51 to 60 of about 413,485 (267)

Hypertension care during the COVID‐19 pandemic in an integrated health care system

The Journal of Clinical Hypertension, 2023
Retention in hypertension care, medication adherence, and blood pressure (BP) may have been affected by the COVID‐19 pandemic. In a retrospective cohort study of 64 766 individuals with treated hypertension from an integrated health care system, we ...
John F. Steiner, J. David Powers, Allen Malone, Jason Lyons, Kari Olson, Andrea R. Paolino, Claudia A. Steiner   +6 more
doaj   +1 more source

Effect of a ward-based outreach team and adherence game on retention and viral load suppression

Southern African Journal of HIV Medicine, 2022
Background: Only 66% of South African people living with HIV (PLWH) are virologically suppressed. Therefore, it is important to develop strategies to improve outcomes.
Sanele Ngcobo, Steve Olorunju, Tshifhiwa Nkwenika, Theresa Rossouw   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Data‐Driven, Patient‐Centred HIV Care Supports Sustained Viral Suppression: A Retrospective Programme Analysis From the Medical Research Foundation of Trinidad and Tobago

Journal of the International AIDS Society
Introduction Achieving and sustaining viral suppression among people living with HIV remains central to global HIV control efforts. Despite global 95–95–95 targets and the scale‐up of differentiated service delivery (DSD) models, many programmes continue
Nyla P. Lyons, Gregory G. Boyce, K. M. Harvey, Wendy Samaroo‐Francis, Brendon M. Bhagwandeen, Robert J. Edwards   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Factors associated with retention in HIV care at Sediba Hope Medical Centre

Southern African Journal of HIV Medicine, 2015
Background: Lost to follow-up (LTFU) is a major challenge that hinders the success of antiretroviral treatment (ART). Objective: To identify factors conducted to a low LTFU rate. Methods: We conducted a two-part descriptive and quantitative study. Part
Nishana Ramdas, Johanna C. Meyer, David Cameron   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

From Pediatric to Adult HIV Care: What Works to Keep Adolescents Engaged—A Systematic Review of Transition Strategies

Tropical Medicine and Infectious Disease
Adolescents living with HIV face unique challenges when transitioning from pediatric to adult care—including stigma, disclosure concerns, and loss of support—that undermine continuity. We systematically searched PubMed, Embase, and Web of Science through
Po-Pin Hung, Hsi-Hsien Wei
doaj   +1 more source