Results 271 to 280 of about 698,339 (387)

A Minimally Invasive Framework Reveals Region‐Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS‐ULM)

Advanced Science, EarlyView.
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri, Adam Nyul‐Toth, Madison Milan, Eva Troyano‐Rodriguez, Sherwin Tavakol, Jennifer Ihuoma, Zeke Reyff, Rakesh Rudraboina, Rafal Gulej, Raymond Jang, Anna Csiszar, Zoltan Ungvari, Audrey Cleuren, David R Miller, Andriy Yabluchanskiy, Mickael Tanter, Stefano Tarantini   +16 more
wiley   +1 more source

DEHYDROGENASES IN THE RETINA AND MÜLLER'S FIBERS [PDF]

, 1959
Toichiro Kuwabara, David G. Cogan, Sidney Futterman, Jin H. Kinoshita   +3 more
openalex   +1 more source

PDZK1 Protects Against RPE Senescence by Targeting the 14‐3‐3ε‐mTOR Axis to Attenuate Early Diabetic Retinopathy

Advanced Science, EarlyView.
PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao, Junbiao Zhang, Yanli Liu, Lili Wang, Chunxi Huang, Wei Chi, Meixia An   +6 more
wiley   +1 more source

Artificial Nervous Systems

Advanced Science, EarlyView.
By drawing inspiration from biological neural hierarchies and the working mechanisms of plasticity, researchers have constructed a series of bionic devices, including sensory devices, synapse devices, and artificial neural systems. They committed to simulating and surpassing the biological information processing function, thereby realizing the ...
Lu Yang, Qingwen Cheng, Yue Li, Ning Wu, Zhipeng Xu, Wentao Xu   +5 more
wiley   +1 more source

High‐Performance Micro‐LED Displays via Etching‐Damage‐Free Pixelation Strategy for Multifunctional Integrated Applications

Advanced Science, EarlyView.
A novel etching‐damage‐free pixelation approach based on F ion implantation has been developed for the fabrication of micro/nano‐LED arrays with a pixel density reaching 25,400 ppi. This method offers the advantages of high resolution, high efficiency, and high brightness, making it highly suitable for applications in near‐eye displays, optical ...
Jinyu Ye, Wenjuan Su, Yibin Lin, Yuyan Peng, Xiongtu Zhou, Tailiang Guo, Jiade Yuan, Jie Sun, Qun Yan, Yongai Zhang, Chaoxing Wu   +10 more
wiley   +1 more source

Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina. [PDF]

Invest Ophthalmol Vis Sci
Nettesheim ER, Rowe AA, Yee T, Alshaikhsalama A, Cepica T, Dutt V, Virani SS, Wickersham G, Mahajan VB, Small KW, Wert KJ.   +10 more
europepmc   +1 more source

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.

Journal of Clinical Investigation, 1998
A. Barber, E. Lieth, S. Khin, D. Antonetti, A. Buchanan, T. Gardner   +5 more
semanticscholar   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Awareness of screening for diabetic retinopathy. [PDF]

Indian J Ophthalmol
Singh R.
europepmc   +1 more source

The mechanism of directionally selective units in rabbit's retina.

Journal of Physiology, 1965
H. Barlow, W. Levick
semanticscholar   +1 more source