Results 291 to 300 of about 409,228 (346)

Sialylation as a checkpoint for inflammatory and complement-related retinal diseases. [PDF]

Front Cell Neurosci
Min Y, Cuevas-Rios G, Langmann T, Neumann H.   +3 more
europepmc   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

OCTA in retina practice - Has it come of age? [PDF]

Indian J Ophthalmol
Bhende M.
europepmc   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Understanding amblyopia from the perspective of neurovascular units: changes in the retina and brain. [PDF]

Front Cell Dev Biol
Zhang L, Zhao Y, Shi X, Wu F, Shen Y.
europepmc   +1 more source

Divergent redox responses of macular and peripheral Müller Glia: Implications for retinal vulnerability. [PDF]

Redox Biol
Zhang T, Jin K, Zeng S, Yang P, Zhu M, Zhang J, Chen Y, Lee S, Yam M, Zeng Y, Lu X, Loo L, Neely GG, Chang A, Zhou F, Du J, Fan X, Zhu L, Gillies MC.   +18 more
europepmc   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Age-related decline in retinal function in marmosets. [PDF]

Sci Rep
Noro T, Guo X, Kikuchi R, Sato K, Namekata K, Shinozaki Y, Harada C, Yurimoto T, Hashimoto N, Moriya-Ito K, Nakano T, Sasaki E, Harada T.   +12 more
europepmc   +1 more source

Characteristics Associated With Endowed Chair Titles Among U.S. Academic Ophthalmologists. [PDF]

Cureus
Choi A, Haystead A, Thompson C, Kundu A, Stinnett SS, Vajzovic L, Fekrat S.   +6 more
europepmc   +1 more source

A Direct and Practical Approach to Assessing the Impact of Emulsion Composition on Vitamin A Stability

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an essential micronutrient involved in vision, immunity, and growth. Despite its widespread use in food, cosmetic, and pharmaceutical products, vitamin A is highly prone to oxidation due to its conjugated double bonds, leading to reduced biological activity and efficacy.
M. De Vreese, E. Durand, B. Baréa, D. Morvan, C. Aleman, J. Lecomte, P. Villeneuve   +6 more
wiley   +1 more source