Results 321 to 330 of about 726,050 (386)

Insights into organelle forming RNAs: Diversity, functions and future perspectives

Animal Models and Experimental Medicine, EarlyView.
RNA molecules play crucial roles in the formation and maintenance of cellular structures and organelles. These ‘organelle formation RNAs’ include ribosomal RNAs, paraspeckle‐forming RNAs, nuclear speckle‐forming RNAs, nucleolus‐forming RNAs, and cytoskeleton‐forming RNA.
Meng Gong, Xiangting Wang, Xiaolin Liang
wiley   +1 more source

Multifocal optical coherence tomography of the mouse eye to image the vitreoretinal vasculature in full depth. [PDF]

J Biomed Opt
Brais-Brunet S, Maltais-Tariant R, Boudoux C, Dehaes M.   +3 more
europepmc   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Annals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh, Kyle C. Kern, Nae‐Yuh Wang, Rebecca F. Gottesman, Clinton B. Wright   +4 more
wiley   +1 more source

Ocular manifestations in autism spectrum disorder. [PDF]

Int J Ophthalmol
Wang NY, Zhu ZY, Jiao ZY, Pan NR, Baig MMI, Qiu AW, Zhang WW.   +6 more
europepmc   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Inner Retina Changes in ABCA4-Related Retinopathy: Structure-Function Relationship. [PDF]

Invest Ophthalmol Vis Sci
Coppé AM, Iarossi G, Cappelli A, Placidi G, Petroni S, Valente P, Novelli A, Maltese P, Bertelli M, Buzzonetti L, Falsini B.   +10 more
europepmc   +1 more source

Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces

Advanced NanoBiomed Research, EarlyView.
Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos, Charlie Hall, Eric J. Hill, Samantha L. Wilson, Paul Roach   +4 more
wiley   +1 more source

Intravitreal Aflibercept for the Treatment of Diabetic Retinopathy Among Patients Who Completed PANORAMA: 1-Year Outcomes from the VOYAGE Extension Study. [PDF]

J Pers Med
Zhou AW, Teagle GM, Baumann LM, Cao JA, Emanuelli A, Hu AY, Berger AS, Major JC, Lee SY, Huddleston SM, Gonzalez VH, Clark WL, Liao DS, Kingsley RM, Lazarus HS, Payne JF, Feinstein EG, Meleth AD, Patel SB, Fan KC, Berliner AJ, Moini H, Niu X, Ip MS, Sadda SR, Al-Khersan H, Wykoff CC.   +26 more
europepmc   +1 more source

Effects of Imposed Defocus on Inhibitor of DNA-Binding Gene Expression in Chick Posterior Ocular Tissues. [PDF]

Cells
Zhang Y, Tseng C, Hang A, Sun D, Song W, Wildsoet CF.   +5 more
europepmc   +1 more source