Morphology and connectivity of retinal horizontal cells in two avian species. [PDF]
Günther A+8 more
europepmc +1 more source
HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis
Abstract Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein. However, in mammalian cells, HN1 is associated partially with y‐tubulin in centrosomes, Stathmin for stabilizing microtubules, and Cdh1 for regulating Cyclin B1 for cell cycle ...
Gülseren Özduman+3 more
wiley +1 more source
A review of rhegmatogenous retinal detachment: past, present and future. [PDF]
Xiong J, Tran T, Waldstein SM, Fung AT.
europepmc +1 more source
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni+9 more
wiley +1 more source
Visual and anatomical outcomes of primary retinectomy for diabetic tractional retinal detachment. [PDF]
Tokuc EO+5 more
europepmc +1 more source
PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah+2 more
wiley +1 more source
Retrospective study of the effectiveness of scleral buckling under direct vision with operating lamp illumination in 17 cases of retinal detachment associated with retinal dialysis. [PDF]
Li S+6 more
europepmc +1 more source
Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”
This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley +1 more source
TRPA1 exacerbates selective retinal ganglion cell vulnerability under acute ocular hypertension. [PDF]
Lu W+11 more
europepmc +1 more source