Results 241 to 250 of about 712,970 (307)

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

Angewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp, Quentin Bertrand, Matilde Trabuco, Anna Duran‐Corbera, Maria Tindara Ignazzitto, Hannah Glover, Fabienne Stierli, Juanlo Catena, Melissa Carrillo, Sina Hartmann, Hans‐Peter Seidel, Matthias Mulder, Thomas Mason, Yasushi Kondo, Maximillian Wranik, Martin Appleby, Christoph Sager, Raymond Sierra, Gregory Gate, Pamela Schleissner, Xinxin Cheng, Tobias Weinert, Robert Cheng, Sandra Mous, John H. Beale, Michal Kepa, Amadeu Llebaria, Michael Hennig, Xavier Rovira, Joerg Standfuss   +29 more
wiley   +1 more source

Neuroanatomical diversity in Teleocichla with new volumetric and histological insights into the encephalon of Teleocichla monogramma Kullander 1988

The Anatomical Record, EarlyView.
Abstract Teleocichla comprises small cichlids that inhabit the rapid streams of Amazonian rivers; however, there has been limited research on their encephalon morphology. This study examined the neuroanatomy of four species, focusing on volumetric measurements of their encephalon subregions, and providing a histological description of the encephalon of
Renan Leão‐Reis, Keila Xavier Magalhães, Thiago Nilton A. Pereira, Janice Muriel‐Cunha, Alberto Akama   +4 more
wiley   +1 more source

Efavirenz treatment improves retinal vaso-obliteration and pathological neovascularization in a mouse model of retinopathy of prematurity. [PDF]

Front Med (Lausanne)
Bailey B, Rudd Zhong Manis J, Seth G, Rajpurohit S, Oxenrider A, Martin PM, Jadeja RN, Thounaojam MC.   +7 more
europepmc   +1 more source

Understanding the spacing of placodes in the eye: A comparative study across age and species

The Anatomical Record, EarlyView.
Abstract The conjunctival placodes of the avian eye form in an intriguing and conserved sequence in a circular annulus around the cornea. These 13–16 placodes develop into papillae that are essential for inducing underlying intramembranous flat bones, known as scleral ossicles, which form an important part of the ocular skeleton.
Florence Joseph, Tamara A. Franz‐Odendaal   +1 more
wiley   +1 more source

Mathematical Modeling of Human Retinal Vascular Pattern Around the Foveal Avascular Zone. [PDF]

Transl Vis Sci Technol
Yoshimura K, Sugihara K, Maruko I, Iida T, Miura T.   +4 more
europepmc   +1 more source

Retinal Images.

Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2006
Keah Say Hien, Chng Kooi Seng
openaire   +2 more sources

Colony-stimulating factor 1 receptor inhibition is neuroprotective to photoreceptors in retinal detachment. [PDF]

Cell Death Dis
Pastor-Puente S, Jung R, Gonzalez-Buendia L, Paschalis EI, Vavvas DG, Kazlauskas A, Maidana DE.   +6 more
europepmc   +1 more source

Advanced therapeutic approaches for inherited retinal diseases: an umbrella review. [PDF]

BMJ Open
Ekemiri K, Daniel E, Seemongal-Dass R, Ekemiri C, Victor V, Amobi M, Adebo O, Tekalign T.   +7 more
europepmc   +1 more source

Short-Term Changes in Retinal Activity With Four Myopia Control Spectacle Lenses. [PDF]

Transl Vis Sci Technol
Fernandes P, Marinho B, Alves-de-Carvalho RS, González-Méijome JM.   +3 more
europepmc   +1 more source

Growth hormone-releasing hormone in retinal disorders and uveitis: an updated review. [PDF]

Int J Ophthalmol
Yi SL, Huang YQ.
europepmc   +1 more source