Inhibition of Caspase-1/Interleukin-1β Signaling Prevents Degeneration of Retinal Capillaries in Diabetes and Galactosemia [PDF]
Jason Vincent, Susanne Mohr
openalex +1 more source
Suggestions for Enhancing the Spatiotemporal Characterization of Retinal Degeneration in the MNU-Induced RP Model [Letter]. [PDF]
Chen C, Gao H, Guo X, Wei W.
europepmc +1 more source
Tracking visual outcomes – Follow‐up on patients born preterm with childhood‐onset visual impairment
Abstract Purpose Preterm birth is associated with a risk of ocular complications. The primary aim of the study was to evaluate the main cause of visual impairment (VI) in a cohort of preterm born patients who had childhood‐onset VI. The association between health‐related quality of life (HRQoL) and age, cause—and severity of VI and impairment type was ...
Hajer A. Al‐Abaiji+4 more
wiley +1 more source
Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration. [PDF]
Omori T+4 more
europepmc +1 more source
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao+5 more
wiley +1 more source
Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase. [PDF]
Dizhoor AM+7 more
europepmc +1 more source
Abstract Background and Objectives Long before any signs of age‐related macular degeneration (AMD) become clinically noticeable, the disease starts with accumulation of deposits of extracellular debris and formation of lesions within the outermost layers of the retina.
Marcus Wagner+3 more
wiley +1 more source
Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration. [PDF]
Fry LE+7 more
europepmc +1 more source
Abstract Purpose To use artificial intelligence (AI) for quantifying schisis volume (ASV) in X‐linked retinoschisis (XLRS) for use as a structural endpoint in gene therapy clinical trials. Methods We used data from Singapore, the United Kingdom, the Netherlands, and the United States. The AI model was developed on 250 optical coherence tomography (OCT)
Tien‐En Tan+10 more
wiley +1 more source
LONGITUDINAL STRUCTURAL CHANGES IN LATE-ONSET RETINAL DEGENERATION
C. Cukras+5 more
semanticscholar +1 more source