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Modeling of retinal degeneration
Bulletin of Experimental Biology and Medicine, 2021We developed a model of retinal degeneration in rabbits based on exposure to light with a wavelength of 405 nm. This model allows reproducing structural and functional disorders in the central parts of the retina, including primarily degeneration of the outer layers of the retina (retinal pigment epithelium and layer of photoreceptor cells), and is ...
A. A. Suetov +4 more
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RETINAL DEGENERATION IN GREYHOUNDS
Australian Veterinary Journal, 1980Retinal degeneration in 10 Greyhounds with clinical and ophthalmoscopic features is described, including results of electroretinography and fluorescein angiography for one affected dog. Clinical and histologic features differed from other kinds of retinal degeneration in dogs.
D. H. Slatter +2 more
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Retinal remodeling during retinal degeneration
Experimental Eye Research, 2005Retinal degenerations, regardless of the initiating event or gene defect, often result in a loss of photoreceptors. This formal deafferentation of the neural retina eliminates the intrinsic glutamatergic drive of the sensory retina and, perhaps more importantly, removes coordinated Ca++-coupled signaling to the neural retina.
Bryan W. Jones, Robert E. Marc
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Nutrition and Retinal Degenerations
International Ophthalmology Clinics, 2000Considerable progress has been made in the understanding and management of degenerative diseases of the retina involving photoreceptors. Nutritional approaches to treatment have proved successful in the case of the common forms of retinitis pigmentosa (supplementation with vitamin A), Bassen-Kornzweig disease (supplementation with vitamins A, E, and K),
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2014
Retinal degenerations are typically characterized by loss of highly differentiated cells within the neurosensory retina, such as photoreceptors, or retinal pigment epithelium (RPE). RPE loss is the final common pathway in a number of degenerations including the leading cause of new blindness in the developed world: age-related macular degeneration ...
Robert Lanza +3 more
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Retinal degenerations are typically characterized by loss of highly differentiated cells within the neurosensory retina, such as photoreceptors, or retinal pigment epithelium (RPE). RPE loss is the final common pathway in a number of degenerations including the leading cause of new blindness in the developed world: age-related macular degeneration ...
Robert Lanza +3 more
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The Vitreo-Tapeto-Retinal Degenerations
Archives of Ophthalmology, 1970Sex-linked recessive and autosomal recessive forms of vitreo-tapeto-retinal degeneration were studied in two families and several isolated cases using psychophysical and electrical tests of retinal function. Common to all affected patients was a progressive retinal degeneration associated with vitreous abnormalities.
Irwin M. Siegel, Ronald E. Carr
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The Retinal Vasculature in Macular Degeneration
Archives of Ophthalmology, 1966A clear understanding of the pathogenesis of macular degeneration would be a major addition to our knowledge of pathology, and more important, would give us the possibility of a rational therapy. Past work on this subject has pointed to changes in the lamina vitrea and changes in the choriocapillaris as possible origins of the breakdown that occurs.1 ...
Abraham L. Kornzweig +2 more
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Sphingolipids and Retinal Degeneration
Science Signaling, 2011Too much dihydrosphingosine 1-phosphate enhances degradation of photoreceptor membrane proteins and leads to retinal degeneration in flies.
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Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.
New England Journal of Medicine, 2017Drs. Toi and Masuda, and other authors of the June 1 article, report being members of the board of the Japan Breast Cancer Research Group. Updated disclosure forms are available with the original article at NEJM.org.
E. Souied, J. Pulido, G. Staurenghi
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Tractional Retinal Degenerations
1988Oral tears occur at the ora serrata, whereas intrabasal tears are located within the vitreous base. Juxtabasal tears are located at the posterior border of the vitreous base. Extrabasal tears are located within the region bounded by the equator and posterior border of the vitreous base.
Keith M. Zinn, Keith M. Zinn
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