Results 111 to 120 of about 68,068 (256)

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

open access: yesJournal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei   +9 more
wiley   +1 more source

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor   +9 more
wiley   +1 more source

Lucid Dreaming Frequency Associated With Grey–White Matter Networks: An Exploratory Multimodal MRI Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Lucid dreaming, defined as the experience of becoming aware of dreaming while dreaming, offers a unique window into a state of consciousness characterised by a blending of the sensory vividness of REM sleep with the self‐awareness of wakefulness. While past functional imaging has shed light on the neural activity supporting lucid dreaming, the
Nicola De Pisapia   +4 more
wiley   +1 more source

Representation, medical examination, and the effectiveness of underwriting: Evidence from a life and health insurance company

open access: yesRisk Management and Insurance Review, EarlyView.
Abstract This study examines whether underwriting methods—representation, medical examination, extra premiums, and coverage—effectively mitigate adverse selection using data from an insurance company. Regarding representation, we focus on statements disclosing pre‐existing medical conditions.
Chia‐Ling Ho   +3 more
wiley   +1 more source

Transconjunctival suprachoroidal buckling for rhegmatogenous retinal detachment. [PDF]

open access: yesInt J Retina Vitreous
El Rayes EN   +3 more
europepmc   +1 more source

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