Results 61 to 70 of about 68,068 (256)

Half-dose verteporfin photodynamic therapy for bullous variant of central serous chorioretinopathy: a case report

Journal of Medical Case Reports, 2011
Introduction Central serous chorioretinopathy is characterized by serous neurosensory detachment of the macula and it usually resolves spontaneously with good visual prognosis.
Lai Timothy YY, Wu Zenith HY, Ng Winnie WK   +2 more
doaj   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source

Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation

Small, EarlyView.
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul, Cédric Bergerbit, Iulia Scarlat, Teodora Piskova, Vasudha Turuvekere Krishnamurthy, Aleksandra N. Kozyrina, Stacy Lok Sze Yam, Laura De Laporte, Jacopo Di Russo   +8 more
wiley   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source

LightMG-Net: an efficient lightweight deep neural network for multiclass grading of retinal detachment using handcrafted statistical mechanisms

Scientific Reports
Retinal detachment is a severely curable eye condition that becomes a genuine factor for the increased visual acuity worldwide. If neglected, it may result significant visual impairment in individuals aged 60 to 69 years.
Sonal Yadav, R. Murugan, Balachandra Pattanaik, Tanveer Ahmed   +3 more
doaj   +1 more source

Management of retinopathy of prematurity in a tertiary referral neonatal intensive care unit: Treatment rates and the impact of outsourcing laser therapy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the treatment rate for retinopathy of prematurity (ROP) at a tertiary referral neonatal intensive care unit (NICU) in the south‐western region of the Netherlands. In addition, we evaluated the impact of outsourcing laser treatment, implemented in 2018, by comparing treatment characteristics from 3 years prior and 3 years ...
L. A. Derks, H. R. Taal, S. E. Loudon, I. K. M. Reiss, J. R. Vingerling, A. M. Tjiam   +5 more
wiley   +1 more source

Management of Giant Retinal Tear with microincision vitrectomy and metallic retinal tacks fixation-a case report

BMC Ophthalmology, 2018
Background Giant retinal tear is usually challenging among retinal detachment with recurrent rate up to 45%. Here we presented a case of giant retinal tear being treated by microincision vitrectomy and retinal tacks fixation.
Yo-Chen Chang, Li-Yi Chiu, Tzu-En Kao, Wen-Hsin Cheng, Ting-An Chen, Wen-Chuan Wu   +5 more
doaj   +1 more source

Axial length, myopia progression, and myopic maculopathy in Stickler syndrome

Acta Ophthalmologica, EarlyView.
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen, Mette Bertelsen, Nanna D. Rendtorff, Stense Farholt, Line Kessel   +4 more
wiley   +1 more source

Surgical techniques in retinal detachment: scleral buckling vs circumferential + buckling

Senses and Sciences, 2017
The goal of surgery for retinal detachment is to repair the detachment obtaining the best results and the minor complications. In cases where retinal rupture has caused excessive subcutaneous fluid accumulation, scleral ...
Fernanda Pacella, Massimo Castellucci, Paolo Turchetti, Aloisa Librando, Raffaele Migliorini, Elena Pacella   +5 more
doaj   +1 more source

Unique Case of Bilateral Exudative Retinal Detachment following Creatine Supplementation in a Patient with Autosomal Dominant Bestrophinopathy

Case Reports in Ophthalmology, 2019
We report a case of bilateral serous retinal detachment in a patient with rod-cone dystrophy caused by mutation of BEST1. This followed creatine monohydrate use as a dietary supplement.
Konstantinos Kopsidas, Hedayat Javidi, Simon P. Kelly, Tariq Aslam, Graeme Black, Sajjad Mahmood   +5 more
doaj   +1 more source