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The Role Gut Microbiota in Glaucoma Progression and Other Retinal Diseases.

American Journal of Pathology, 2023
As a rapidly growing field, microbiota research offers novel approaches to promoting ocular health and treating major retinal diseases, such as glaucoma.
Julie Chen, D. Chen, Kin-Sang Cho
semanticscholar   +1 more source

Interleukin-6 in retinal diseases: From pathogenesis to therapy.

Experimental Eye Research, 2023
Interleukin-6 (IL-6) is a pleiotropic cytokine that participates in immunomodulation, inflammation, increases vascular permeability, hematopoiesis, and stimulates cell proliferation, among other biological processes.
Ruihan Xiao   +3 more
semanticscholar   +1 more source

Role of m6A methylation in retinal diseases.

Experimental Eye Research, 2023
Retinal diseases remain among the leading causes of visual impairment in developed countries, despite great efforts in prevention and early intervention.
Xinyue Zhu   +3 more
semanticscholar   +1 more source

Inherited retinal diseases: Linking genes, disease-causing variants, and relevant therapeutic modalities.

Progress in retinal and eye research, 2021
Inherited retinal diseases (IRDs) are a clinically complex and heterogenous group of visual impairment phenotypes caused by pathogenic variants in at least 277 nuclear and mitochondrial genes, affecting different retinal regions, and depleting the vision
Nina Schneider   +8 more
semanticscholar   +1 more source

Gene therapy for inherited retinal diseases: progress and possibilities

Clinical and experimental optometry, 2021
Inherited retinal diseases (IRDs) comprise a heterogeneous group of genetic disorders affecting the retina. Caused by mutations in over 300 genes, IRDs result in visual impairment due to dysfunction and degeneration of photoreceptors, retinal pigment ...
Monica L Hu   +6 more
semanticscholar   +1 more source

The emerging role of the Angiopoietin-Tie pathway as therapeutic target for treating retinal diseases

Expert opinion on therapeutic targets, 2022
Introduction Several approaches have been investigated for treating wet age-related macular degeneration (w-AMD), diabetic macular edema (DME) and retinal vein occlusions (RVOs).
L. Ferro Desideri   +2 more
semanticscholar   +1 more source

Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod dystrophies, rod-cone dystrophies, leber congenital amaurosis, and cone dysfunction syndromes.

Progress in retinal and eye research
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population and children. The scope of this review is to familiarise clinicians and scientists with the current landscape of molecular genetics, clinical phenotype ...
M. Georgiou   +10 more
semanticscholar   +1 more source

Retinal Vascular Diseases

Occupational Health Nursing, 1983
The eye can be affected by obstructive phenomena within large vessels, such as the corotid arteries, as well as in the ophthalmic artery, central retinal artery, and branch retinal arteries. The visual impairment seen with central retinal vein obstruction usually occurs over a period of days to weeks, and although vision improves spontaneously in some ...
openaire   +3 more sources

Hereditary retinal disease

Current Opinion in Ophthalmology, 2008
This article reports recent advances in the diagnosis, genetic analysis, and treatment of hereditary retinal disease.Clinicians and scientists continue to reveal the relationship between phenotype and genotype in hereditary retinal diseases. Persistent investigation and progressive technology are advancing the efficiency of mutation discovery.
openaire   +2 more sources

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